YORK — Four people were injured in a Route 1 crash Wednesday night, and police arrested one driver for operating under the influence.

According to York police, a 2005 Dodge Caravan, driven by Kenneth Ross, 30, of Bristol, N.H., hit the rear of a 2005 Saab driven by Jeremy Mirick, 33, of York, as both cars were headed southbound on Route 1 near the entrance to York’s Wild Kingdom.

The impact caused Ross to lose control of his van, and he crossed into the northbound lanes, hitting a 2001 Saab driven by Christopher Cawley, 19, of Ogunquit, head-on. The van continued on and hit a 2002 Chevrolet driven by Kenneth M. Stitt, 21, of York.

Cawley was the most seriously injured, with a broken leg, and head and neck injuries. He was taken to Maine Medical Center. Keisi L. Eames, 19, of North Berwick, a passenger in Cawley’s car, had cuts and bruises and was treated and released from York Hospital. Stitt was treated for minor injuries at York Hospital and released. Ross had a broken foot and was treated and released from York Hospital.

Police said Ross was charged with operating under the influence and taken to York County Jail, where he was being held in lieu of $500 cash bail.