WASHINGTON — The government scrambled Tuesday to prevent future spills of U.S. secrets like the embarrassing WikiLeaks’ disclosures, while officials pondered possible criminal prosecutions.

In Europe, Interpol placed the website’s founder, Julian Assange, on its most-wanted list after Sweden issued an arrest warrant against him as part of a drawn-out rape probe – involving allegations Assange has denied. The Interpol alert is likely to make international travel more difficult for Assange, whose whereabouts are publicly unknown.

In Washington, the State Department severed its computer files from the government’s classified network, officials said, as U.S. and world leaders tried to clean up from the leak that sent America’s sensitive documents onto computer screens around the globe.

temporarily pulling the plug, the U.S. significantly reduced the number of government employees who can read important diplomatic messages.

The documents revealed that the U.S. is still confounded about North Korea’s nuclear military ambitions, that Iran is believed to have received advanced missiles capable of targeting Western Europe and – perhaps most damaging to the U.S. – that the State Department asked its diplomats to collect DNA samples and other personal information about foreign leaders.

While Assange, the founder of WikiLeaks, taunted the U.S. from afar on Tuesday, lawyers from across the government were investigating whether it could prosecute him for espionage, a senior defense official said. The official, not authorized to comment publicly, spoke only on condition of anonymity.

There have been suggestions that Assange or others involved in the leaks could be prosecuted under the Espionage Act, but the question could be complicated because of the nature of the Internet.

Meanwhile, State Department spokesman P.J. Crowley sought to reassure the world that U.S. diplomats were not spies, even as he sidestepped questions about why they were asked to provide DNA samples, iris scans, credit card numbers, fingerprints and other deeply personal information about leaders at the United Nations and in foreign capitals.

Diplomats in the Paraguayan capital of Asuncion, for instance, were asked in a secret March 2008 cable to provide “biometric data, to include fingerprints, facial images, iris scans, and DNA” for numerous prominent politicians. They were also asked to send “identities information” on terrorist suspects, including “fingerprints, arrest photos, DNA and iris scans.”

In Burundi, Rwanda and the Democratic Republic of Congo the requests included information about political, military and intelligence leaders.

“Data should include e-mail addresses, telephone and fax numbers, fingerprints, facial images, DNA, and iris scans,” the cable said.

Every year, the intelligence community asks the State Department for help collecting routine information such as biographical data and other “open source” data. DNA, fingerprint and other information was included in the request because, in some countries, foreigners must provide that information to the U.S. before entering an embassy or military base, a U.S. official said, speaking on condition of anonymity to discuss intelligence matters.

The possibility that American diplomats pressed for more than “open source” information has drawn criticism at the U.N. and in other diplomatic circles over whether U.S. information-gathering blurred the line between diplomacy and espionage.

“What worries me is the mixing of diplomatic tasks with downright espionage. You cross a border … if diplomats are encouraged to gather personal information about some people,” U.N. Secretary-General Ban Ki-moon said.