BIDDEFORD — A fire of undetermined origin destroyed the interior of a home at 25 Duffy’s Way this afternoon.

Lt. David Dutremble said that when firefighters arrived – around 3:15 p.m. – the fire had begun to spread from the first floor to the second floor of the two-story, wood frame home.

No one was home at the time, Dutremble said. The homeowner’s name was not available.

The cause of the fire remains under investigation.