CHICAGO – Jose Quintana took a no-hitter into the seventh before David Ortiz broke it up with a one-out broken-bat single, and the Chicago White Sox beat a late-inning downpour and the Boston Red Sox with a 3-1 win on Tuesday night.

Jeff Keppinger hit a two-run homer off Felix Doubront (3-2) in the fifth. Alex Rios extended his career-high hitting streak to 16 with a single and RBI double, and the White Sox won for the sixth time in eight games. They’ll try to complete the sweep against Clay Buchholz on Wednesday.

Quintana (3-1) was simply terrific.

The left-hander struck out five and walked two, and had the fans thinking they just might be witnessing something special.

The roars from the stands grew louder with each out as the game wore on, right until Ortiz’s bat shattered on a bloop single to center with one out in the seventh.

That ended the bid for the 19th no-hitter in White Sox history and the first since Philip Humber’s perfect game at Seattle on April 21 last season.

Two more singles by Mike Napoli and Daniel Nava loaded the bases and ended the night for Quintana, who got a standing ovation as he left the field.

Jesse Crain came on to strike out Will Middlebrooks and Stephen Drew to end that threat, but the Red Sox got a run in the eighth after Matt Thornton walked Jarrod Saltalamacchia leading off and gave up a single to Jacoby Ellsbury.

Matt Lindstrom retired pinch-hitter Mike Carp on a fly to left before uncorking a wild pitch, and Saltalamacchia scored from third when shortstop Alexei Ramirez allowed Dustin Pedroia’s hard grounder to go through his legs for an error.

Ortiz then grounded into a double play to end the rally, and Rios added an RBI double in the bottom half to make it a two-run game.

Addison Reed worked the ninth for his 16th save in 17 chances, although Casper Wells had a bit of an adventure in left. He slipped while catching Nava’s fly to warning track for the second out before Middlebrooks ended it with a fly to center.

Doubront was a tough-luck loser even though he was almost as effective as Quintana. He allowed two runs and five hits and walked two.

NOTES: The White Sox scratched Chris Sale from Wednesday’s start against the Red Sox because of a mild tendinitis in his left shoulder.

Sale was scheduled to pitch against the unbeaten Clay Buchholz (6-0, 1.78 ERA).

He will make his next scheduled start against the Cubs on Tuesday.