Missed the chance to bid on Francis Crick’s Nobel Prize when it was auctioned off last year for $2.27 million?

No worries, you’ll have another chance to own a piece of science history on Dec. 4, when James D. Watson’s 1962 Nobel Prize, shared with Crick and Maurice Wilkins for their work characterizing the double-helix structure of DNA, goes under the hammer at the New York auction house Christie’s.

Better make sure your bank account can handle it though: After the $6 million sale last year of a letter written by Crick to his son that described the team’s discovery, Christie’s is estimating that Watson’s Nobel Prize could demand up to $3.5 million.

No other Nobel Prize has been offered for sale by a living recipient, Christie’s said. The auction house said Watson planned to donate a portion of the proceeds “to continue his philanthropic legacy of supporting scientific research, academic institutions and other charitable causes.”

The 1953 discovery of DNA’s double-helix design is considered one of modern science’s watershed moments, giving birth to a new science of molecular biology and leading to extraordinary advances in medicine.

The medal given to Watson was minted at the Swedish National Mint and is plated with 24 karat gold. Watson, now 86, is chancellor emeritus of Cold Spring Harbor Laboratory in Cold Spring Harbor, N.Y.