BEIRUT —A cease-fire brokered by the United States and Russia went into effect across Syria on Saturday, marking the biggest international push to reduce violence in the country’s devastating conflict, but the Islamic State group and al-Qaida’s branch in Syria, the Nusra Front, were excluded.

The cease-fire aims to bring representatives of the Syrian government and the opposition back to the negotiating table in Geneva for talks on a political transition. The U.N.’s envoy, Staffan de Mistura, announced that peace talks would resume on March 7 if the cessation of hostilities “largely holds.”

If it does, it would be the first time international negotiations have brought any degree of quiet in Syria’s five-year civil war. But success requires adherence by multiple armed factions – and the truce is made more fragile because it allows fighting to continue against the Islamic State group and Nusra Front, which could easily re-ignite broader warfare.

The Syrian government and the opposition, including nearly 100 rebel groups, have said they will abide by the cease-fire.

Speaking to reporters in Geneva after the truce took hold at midnight, de Mistura said initial reports indicated that within minutes both Damascus and the nearby rebel-held town of Daraya suddenly “had calmed down.” He said there was a report of one “incident” that his team was investigating but did not give details.


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