LSU fired Coach Les Miles and offensive coordinator Cam Cameron on Sunday, and promoted defensive line coach Ed Orgeron to interim head coach.

The moves came less than 24 hours after Miles briefly watched his players celebrate what they thought was a last-second winning touchdown pass at Auburn, only to walk off the field with a loss after officials determined on video replay that time had expired before the ball was snapped.

It was the latest of several frantic finishes in which the clock management of a Miles-coached offense had come under intense scrutiny. It will go down as the last.

“Coach Miles has done a tremendous job here and he’s been a great ambassador for our University, which makes this even more difficult,” LSU Athletic Director Joe Alleva said in a written statement. “However, it’s apparent in evaluating the program through the first month of the season that a change has to be made.

“We have an obligation to our student-athletes to put them in the best position to have success on the football field each week. We have great confidence that Coach Orgeron will do just that.”

Miles’ firing, reported first by The Advocate of Baton Rouge, came hours after LSU (2-2, 1-1 Southeastern Conference), which was ranked 18th last week, dropped out of the Top 25 in the latest AP Poll released Sunday afternoon.

Miles, who was in his 12th season, went 114-34 at LSU, the second-most victories in school history behind Charles McClendon’s 137 victories from 1962 to 1979.

Cameron, an old friend of Miles from when they were both assistants at Michigan in the 1980s, joined LSU in 2013. His offense was largely effective when his quarterback was Zach Mettenberger, a tall, strong-armed pro-style pocket passer. Production was far less consistent – and the passing game was often anemic – during the past two seasons.

NOTRE DAME: Coach Brian Kelly fired defensive coordinator Brian VanGorder, hours after an embarrassing 38-35 home loss to Duke dropped the Fighting Irish – who started the season ranked No. 10 – to 1-3.

Greg Hudson, a former Irish linebacker under Lou Holtz who was hired as a defensive analyst over the summer, was named VanGorder’s replacement.

TOP 25: Wisconsin moved up to No. 8 in The Associated Press college football poll and LSU became the second preseason top-10 team to drop out of the rankings in the first month of the season.

There were few changes in the Top 25 as the only four ranked teams that lost did so to other ranked teams.

The top teams held their spots, led by No. 1 Alabama. The Crimson Tide received 50 first-place votes. No. 2 Ohio State was followed by Louisville, Michigan, Clemson, Houston and Stanford.

Wisconsin moved up three spot after dominating Michigan State 30-6. Texas A&M moved up a spot to No. 9.

LSU (2-2), which started the season No. 5, joined Notre Dame as preseason top-10 teams to fall out of the poll.