LONDON — The New York Giants capitalized on four interceptions of Case Keenum to defeat the Los Angeles Rams 17-10 Sunday in the first NFL game played at London’s home of English rugby, a sold-out and raucous Twickenham Stadium.

Keenum, coming off the best start of his career, had the Rams at the Giants 15 with 50 seconds left when he lobbed a pass to the left corner of the end zone that Dominique Rodgers-Cromartie easily picked off. Keenum’s intended target, Brian Quick, failed to get the quarterback’s audible and cut off his route early.

Keenum, who was 32 of 53 for 291 yards and one touchdown, has thrown an interception on the Rams’ final offensive play in three straight games. That likely will fuel debate on a potential quarterback change to overall No. 1 draft pick Jared Goff.

The win kept the Giants (4-3) in good shape in the NFC East, where no one has a losing record. The Rams (3-4) lost their third straight.

CHARGERS 33, FALCONS 30: Josh Lambo’s 42-yard field goal in overtime gave San Diego (3-4) its first road win of the year as the Chargers rallied from a 17-point deficit.

San Diego, which trailed 27-10 in the second quarter, had lost 11 of its previous 12 road games.

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Linebacker Denzel Perryman’s interception of Matt Ryan’s pass for Julio Jones set up Lambo’s tying 33-yard field goal with 18 seconds remaining in regulation.

Perryman’s fourth-and-1 stop on running back Devonta Freeman gave San Diego the ball at Atlanta’s 43, setting up the winning field goal.

CHIEFS 27, SAINTS 21: Alex Smith threw two touchdown passes in another efficient outing, and Daniel Sorensen returned an interception of Drew Brees for another touchdown as Kansas City (4-2) won its ninth straight at home.

Brees got the Saints (2-4) within 24-21 with his touchdown pass to Brandon Coleman with 2:33 left, but the onside kick went out of bounds. Brees finished with 367 yards and three TD passes.

RAIDERS 33, JAGUARS 16: Latavius Murray scored twice in his return from turf toe, and Oakland (5-2) gave Coach Jack Del Rio a road victory against his former team.

The Jaguars (2-4) dropped their third straight home game and added more speculation about the future of Coach Gus Bradley. Jacksonville is 14-40 during Bradley’s four seasons.

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LIONS 20, WASHINGTON 17: Matthew Stafford threw a go-ahead, 18-yard touchdown pass to Anquan Boldin with 16 seconds left, and Detroit (4-3) extended its winning streak to three games.

Visiting Washington (4-3) had won four straight.

Kirk Cousins scored a go-ahead TD on a 19-yard run with 1:05 left.

BENGALS 31, BROWNS 17: A.J. Green’s one-handed 48-yard touchdown catch in the middle of an end zone scrum at the end of the first half highlighted a day full of big plays for Cincinnati (3-4).

Jeremy Hill had a 74-yard touchdown run as part of his 168-yard effort, the best by a Bengals back in seven years.

The visiting Browns (0-7) extended their worst start since 1999, when they were a first-year expansion team.

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COLTS 34, TITANS 26: Andrew Luck threw a 7-yard touchdown pass to Jack Doyle with 1:55 left to put visiting Indianapolis (3-4) ahead to stay, and the Colts rallied for their 10th straight win against their AFC South rival.

Luck finished with 353 yards passing and three TDs, the last after Tennessee (3-4) went up 23-20.

JETS 24, RAVENS 16: Ryan Fitzpatrick replaced an injured Geno Smith and led the Jets (2-5) on three scoring drives, and a rejuvenated defense came up with two interceptions against visiting Baltimore (3-4).

Fitzpatrick entered in the second quarter and directed a go-ahead drive capped by Matt Forte’s 13-yard touchdown catch. Fitzpatrick finished 9 of 14 for 120 yards as the Jets snapped a four-game losing streak.

Joe Flacco started for Baltimore (3-4), loser of four in a row, after being questionable because of a sore shoulder.

BUCCANEERS 34, 49ERS 17: Jameis Winston threw three touchdown passes and Jacquizz Rodgers ran for 154 yards as visiting Tampa Bay (3-3) dealt San Francisco (1-6) its sixth straight loss.

Colin Kaepernick struggled in his second start of the season for the 49ers, going 16 of 34 for 143 yards and turning the ball over twice.


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