DUBAI, United Arab Emirates — Emirates, the Middle East’s largest airline, slashed its flights to the United States by 20 percent Wednesday, blaming a drop in demand on tougher U.S. security measures and Trump administration attempts to ban travelers from some Muslim-majority nations.

The Dubai government-owned carrier’s decision is the strongest sign yet that new measures imposed on U.S.-bound travelers from the Mideast could be taking a financial toll on fast-growing Gulf carriers that have expanded rapidly in the U.S.

Dubai was one of 10 cities in Muslim-majority countries affected by a ban on laptops and other personal electronics in carry-on luggage aboard U.S.-bound flights.

Emirates’ hub at Dubai International Airport, the world’s third-busiest, is also a major transit point for travelers who were affected by President Trump’s executive orders temporarily halting entry to citizens of six countries.

The latest travel ban suspended new visas for people from Iran, Libya, Somalia, Sudan, Syria and Yemen, and froze the nation’s refugee program. Like an earlier ban that also included Iraqi citizens, it has been blocked from taking effect by the courts.

Emirates said the flight reductions will affect five of its 12 U.S. destinations, with the first cutbacks starting next month.

“The recent actions taken by the U.S. government relating to the issuance of entry visas, heightened security vetting, and restrictions on electronic devices in aircraft cabins, have had a direct impact on consumer interest and demand for air travel into the U.S.,” the carrier said in a statement.

Emirates does not provide financial data for its U.S. operations or individual routes, but said it had seen “healthy growth and performance” there until the start of the year.

Since Trump has been in office, however, there has been what it called “a significant deterioration in the booking profiles on all our U.S. routes, across all travel segments.”

It said it is responding as “any profit-oriented enterprise would” and will use the capacity freed up by the culled routes elsewhere on its network.

The Americas region, which also includes routes to Canada and Latin America, accounted for 14 percent of the $22.75 billion in revenue Emirates pulled in during the fiscal year through the end of March 2016.

Emirates’ half-year profit fell 75 percent to $214 million in the last period the company has disclosed, through September. Executives cited increased investments including aircraft purchases and the repayment of bonds, and said a “bleak” economic outlook in much of the world was reducing demand.