Penn State climbed to No. 2 in The Associated Press College football poll behind unanimous No. 1 Alabama after a wild weekend of upsets that gave the Top 25 a major makeover.

A season-high seven ranked teams, including four in the top 10, lost to unranked teams on Friday and Saturday. Defending national champion Clemson and defending Pac-12 champion Washington were the highest-ranked teams to lose.

Penn State, which was idle, took advantage. The Nittany Lions moved up a spot to No. 2, 15 points ahead of No. 3 Georgia. Penn State has its best ranking since Oct. 31, 1999, when the Nittany Lions were No. 2.

Alabama, which has been No. 1 since the preseason, received all 61 first-place votes for the first time this year.

TCU is No. 4, Wisconsin is No. 5, and Big Ten rival Ohio State is sixth.

Clemson dropped five spots to seventh. Miami, Oklahoma and Oklahoma State round out the top 10.

Clemson started the weekend’s weirdness on Friday night at Syracuse, losing a three-point game as three-touchdown favorites. Washington State followed that up by getting routed at California later Friday, dropping the Cougars from eighth place to 15th.

On Saturday, the strangeness continued: No. 10 Auburn lost at LSU after leading 20-0 in the second quarter. No. 19 Michigan, No. 8 Miami and No. 9 Oklahoma all barely dodged the upset bug, and No. 11 USC rallied to beat Utah. Then came maybe the biggest stunner of all: Washington lost at Arizona State, scoring seven points against a team that had not given up fewer than 30 since last season.

Also, Texas Tech blew an 18-point fourth-quarter lead against West Virginia, and Navy and San Diego State each lost for the first time.