May 14, 2013

Jolie admired for bravery in mastectomy revelation

The Oscar-winning actress says she made the choice with thoughts of her six children after watching her own mother, actress Marcheline Bertrand, die too young from cancer.

The Associated Press

LOS ANGELES —  "I hope that other women can benefit from my experience," Angelina Jolie wrote in a powerful op-ed article Tuesday, explaining her decision to go public with having her breasts removed to avoid cancer.

click image to enlarge

Angelina Jolie: "I do not feel any less of a woman. I feel empowered that I made a strong choice that in no way diminishes my femininity."

AP

Related headlines

But amid the accolades for the film star's courageous revelation, doctors and genetic counselors were careful to note that her medical situation — an inherited genetic mutation putting her at high risk of breast and ovarian cancer — was very specific, and that her course of action made sense for only a small category of women.

Still, they hailed her bravery and said that she would surely help increase awareness — and thus, perhaps, help save some lives.

"Having this conversation empowers us all," said Rebecca Nagy, a genetic counselor who works frequently with women who test positive for a defective version of the BRCA1 gene, as Jolie did. "It's wonderful what she's done."

In a stunning op-ed piece in the New York Times, Jolie, 37, began by speaking of her late mother, Marcheline Bertrand, who died of cancer at 56, before she was able to meet most of her grandchildren.

The actress revealed that beginning in February, she underwent three surgeries — which she succeeded in keeping secret from the public — in which her breasts were removed, and later replaced by implants.

"I wanted to write this to tell other women that the decision to have a mastectomy was not easy. But it is one I am very happy that I made," Jolie wrote. "My chances of developing breast cancer have dropped from 87 percent to under 5 percent. I can tell my children that they don't need to fear they will lose me to breast cancer."

The actress also hinted that she might, at some point, have her ovaries removed, saying that she had "started with the breasts" because her risk of breast cancer was higher than that for ovarian cancer. She did not say how long ago she was diagnosed with the faulty gene.

While admiring Jolie's straightforwardness, cancer surgeons and others in the medical community were quick to point out that hereditary cases of breast cancer account for only about 5 percent to 7 percent of all cases diagnosed each year. And those connected to the BRCA1 and BRCA2 genes are an even smaller group.

And so, women shouldn't just run off and get tested for those genes, said Dr. Robert Shenk, medical director of the Breast Center at the University Hospitals Case Medical Center in Cleveland.

"My worry is that people will be inappropriately tested," said Shenk. "Awareness is great, but people shouldn't just run in off the street and get a test."

Instead, he said, genetic counseling, including a close review of a patient's family history, is crucial.

Nagy, the genetic counselor, who is also president of the National Society of Genetic Counselors, agreed.

"The clues are in the family history. Has there been cancer in multiple generations?" she said. "Are there clusters of cancers, like breast and ovarian, on the same side of the family? Has the cancer been diagnosed at an early age — under 50?"

If those factors exist, Nagy said, she conducts a thorough risk assessment with the patient. And if testing is warranted, there still needs to be some thought beforehand as to what one might do with the information.

(Continued on page 2)

Were you interviewed for this story? If so, please fill out our accuracy form

Send question/comment to the editors




Further Discussion

Here at PressHerald.com we value our readers and are committed to growing our community by encouraging you to add to the discussion. To ensure conscientious dialogue we have implemented a strict no-bullying policy. To participate, you must follow our Terms of Use.

Questions about the article? Add them below and we’ll try to answer them or do a follow-up post as soon as we can. Technical problems? Email them to us with an exact description of the problem. Make sure to include:
  • Type of computer or mobile device your are using
  • Exact operating system and browser you are viewing the site on (TIP: You can easily determine your operating system here.)