Monday, March 10, 2014
By Matt Hongoltz-Hetling email@example.com
The patient, who had cancer, had come down with some flu-like systems.
It was 2008 and Tim Borelli, now a physician who specializes in infectious diseases at MaineGeneral Health Center in Augusta, was in his fellowship at the time.
“She had an illness,” he said. “It was kind of nonspecific.”
The patient’s symptoms ordinarily wouldn’t be cause for alarm, but because the woman was weakened by cancer, Borelli took them seriously.
“We tested her for all kinds of things,” he said. “We look for all possible causes. We check their lungs to make sure they don’t have pneumonia. We do physical exams. Do they have any rashes?”
Tests of her urine showed nothing. Her X-ray was clear. She had no skin infections or stomach problems.
“Then you have to start thinking about different possibilities, such as viral or tick-borne diseases,” Borelli said. “It was in a summer month. Tick-borne diseases are always things we need to consider. And we learned she had had some tick exposure.”
Some of the blood work showed that the woman’s blood didn’t have enough white blood cells in it. Tests also revealed a high level of liver enzymes in the blood, most commonly seen when the liver is damaged or inflamed.
Taken together, the two things pointed to anaplasmosis.
A tick bite usually spurs thoughts of Lyme disease, but a recent rise in anaplasmosis has caught the attention of epidemiologists in the state.
Many people shrug off the effects of anaplasmosis – symptoms can include fever, chills, fatigue, a headache or muscle pain – but in rare cases, especially for those with compromised immune systems, it can kill.
The woman’s diagnosis wouldn’t have been a problem for the majority of people. Most healthy people don’t even require treatment. A two-week course of doxycycline, the same antibiotic that is used to treat Lyme disease, usually kills the bacteria for those who do need treatment.
But Borelli’s patient’s system was already so weak that it was the final blow.
“She did succumb to that illness,” Borelli said. “That was a sad case.”
The anaplasmosis wasn’t considered the cause of death, he said, but it was a contributing factor.
Anyone whose spleen has been removed, who has had a bone marrow transplant or undergone chemotherapy and then gets anaplasmosis is at risk, Borelli said.
About one in 200 people who are diagnosed with the disease dies as a result of it, according to the Centers for Disease Control and Prevention.
TICK ATTACKS LETTERMAN
About a year after Borelli lost a patient to anaplasmosis, David Letterman, host of “The Late Show” on CBS, told millions of viewers in late July 2009 that he was sick, but he didn’t tell them what he was suffering from, touching off widespread speculation about what it could be.
For a few days in a row, he took his temperature on air, which was more than 100 degrees one night and which topped out at 102.5. He joked that the thermometer reading meant someone won $100 in a pool among the show’s staffers.
That Thursday, he told the audience that he was recovering from anaplasmosis, which he said he probably contracted from a tick while spending the night in a treehouse with his son. He said it left him feeling worse than he had in the aftermath of heart bypass surgery.
Letterman’s experience taught many the name of the disease just when it was starting to become more common in the United States, mostly in the upper Midwest and Northeast regions.
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