So much for the NFL’s unbeatens.

The Denver Broncos and New England Patriots (See B1) took care of that with impressive home victories over the Arizona Cardinals and Cincinnati Bengals on Sunday.

Peyton Manning had four TD throws and Denver (3-1) gained 568 yards the Broncos’ 41-20 victory over the Cardinals.

“He’s not in the history books for nothing,” Arizona cornerback Patrick Peterson said. “He just came out here and lit us up.”

Broncos 41, Cardinals 20

Manning joined Brett Favre with at least 500 touchdown passes and is closing in on Favre’s record. Manning moved within five of Favre’s 508. Manning found tight end Julius Thomas twice in the end zone, including the touchstone touchdown, a 7-yard dart in the first quarter.

“Football is the ultimate team game, and so I guess one man has to accept it and I really accept it on behalf of a lot of coaches and teammates,” Manning said.

Manning threw for 479 yards, and Demaryius Thomas set a franchise record with 226 yards on eight catches, beating Shannon Sharpe’s mark of 214 yards set against Kansas City in 2002.

Wes Welker’s seven receptions moved him past Rod Smith for the most catches in NFL history by an undrafted player. He has 854.

Cowboys 20, Texans 17, OT

Dan Bailey kicked a 49-yard field goal in overtime after a miss at the end of regulation ended his franchise record streak of made kicks. Bailey’s kick was set up when Tony Romo threw off his back foot and Dez Bryant made a spectacular leaping catch for 37 yards.

The host Cowboys (4-1) have won fourth straight for the first time since 2011. The Texans (3-2) rallied behind Arian Foster, who had 157 yards rushing and a tying 1-yard score with 41 seconds left in regulation.

Browns 29, Titans 28

Brian Hoyer threw a 6-yard touchdown pass to Travis Benjamin with 1:09 left, and the Browns rallied from a 25-point deficit for the biggest comeback in franchise history and the NFL’s largest comeback by a road team.

The Browns (2-2) had never rallied from more than 20 points, and easily topped the comeback on Dec. 4, 1966, when Cleveland trailed the Giants 34-14 and won 49-40, according to STATS.

Saints 37, Bucs 31, OT

At New Orleans, Khiry Robinson’s tackle-breaking, 18-yard touchdown run in overtime won it.

Pierre Thomas caught eight passes out of the backfield for 77 yards and a touchdown. He also rushed for 35 yards and a score to help New Orleans (2-3) overcome Drew Brees’ three interceptions — and an 11-point deficit in the fourth quarter.

Brees completed 35 of 57 passes for 371 yards and two touchdowns, but two of his interceptions led directly to Buccaneers touchdowns. His third ended a potential winning drive in the final minute of regulation.

Making his second straight start for Tampa Bay (1-4), Mike Glennon was 19 for 32 for 249 yards and two touchdowns.

Bill 17, Lions 14

At Detroit, Dan Carpenter hit a 58-yard field goal with four seconds remaining.

Kyle Orton, making his debut as Bills starter, went 30 of 43 for 308 yards with a 2-yard touchdown pass to Chris Gragg as Buffalo (3-2) overcame a 14-0 deficit. It was the eighth game Orton has won in overtime or when trailing in the fourth quarter.

49ers 22, Chiefs 17

Phil Dawson kicked five field goals, while Frank Gore ran for 107 yards and the host 49ers (3-2) converted a fake punt.

On fourth-and-1 from their 29 early in the fourth quarter, a direct snap to Craig Dahl resulted in a 3- yard run up the middle. Dawson kicked a 27-yarder with 8:42 to play for the go-ahead score. Dawson also connected from 55, 52, 35 and 30 yards.

Chargers 31, Jets 0

At San Diego, Philip Rivers threw two touchdown passes to Antonio Gates and rookie running back Branden Oliver’s big day included his first two NFL touchdowns.

The Chargers (4-1) heaped more pain on the Jets (1-4), who lost their fourth straight game and turned to Michael Vick at quarterback. Vick replaced Geno Smith on New York’s first possession of the second half, but wasn’t any more effective in the NFL’s first shutout this season.

Panthers 31, Bears 24

Cam Newton threw two touchdown passes to Greg Olsen and the Panthers’ defense forced four turnovers to overcome a 14-point deficit.

With the game tied at 24, Carolina’s Antoine Cason stripped Matt Forte of the ball and the Kawaan Short recovered at Chicago’s 23. Six plays later, Newton found Olsen on a slant route for a 6-yard touchdown.

The Panthers sealed the win when Short sacked Jay Cutler and Charles Johnson recovered a fumble as the Panthers (3-2) snapped a two-game losing streak.

Eagles 34, Rams 28

The Eagles (4-1) rebounded from a loss at San Francisco with a strong all-around performance until the Rams came on at the end. Chris Maragos returned a blocked punt for a touchdown, Cedric Thornton recovered a fumble for a score and nearly took another one the distance.

Colts 20, Ravens 13

At Indianapolis, Andrew Luck threw one touchdown pass and ran for another score and the defense held on late. Luck was 32 of 49 for 312 yards with two interceptions, but scored the winning points on a nifty 13-yard run with 8:56 left.

Indianapolis (3-2) has won three straight. Baltimore (3-2) lost for the first time since Week 1.

Giants 30, Falcons 20

First-round draft pick Odell Beckham Jr. made his NFL debut, catching a go-ahead 15-yard touchdown pass from Eli Manning.

Fellow rookie Andre Williams scored on a 3-yard run to ignite the second-half rally that saw the host Giants (3-2) come from 10 points down to win their third straight game.

Steelers 17, Jags 9

Brice McCain returned an interception 22 yards for a touchdown. McCain stepped in front of receiver Allen Hurns early in the fourth quarter, intercepted rookie Blake Bortles’ wobbly sideline pass and went untouched the other way.

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