GREEN BAY, Wis. — Another fast start at home for the Green Bay Packers left the Philadelphia Eagles with a loss in the cold.

Aaron Rodgers passed for 341 yards and three touchdowns, Julius Peppers returned his second interception of the season for a score, and the Packers defense stuffed the high-octane Eagles for a 53-20 rout Sunday.

The matchup of NFC contenders quickly became a blowout, with the Packers (7-3) racing out to a 30-6 halftime lead. Rodgers threw for two touchdowns in the first half, and Micah Hyde scored on a 75-yard punt return.

Peppers finished off the Eagles (7-3) by returning an interception 52 yards in the third quarter.

RAMS 22, BRONCOS 7: Shaun Hill was effective in his first start since regaining the quarterback job and the St. Louis defense made life miserable for Peyton Manning in a victory over visiting Denver (7-3).

Tre Mason rushed 29 times for 113 yards, the most allowed by the Broncos’ top-ranked run defense. Kenny Britt had four catches for 128 yards with a 63-yard score, and Greg Zuerlein was a career-best 5 for 5 on field goals for the Rams (4-6).

Manning was 34 for 54 for 389 yards with two interceptions, but was held to a 42-yard touchdown pass to Emmanuel Sanders, ending a streak of 15 consecutive games with at least two touchdown passes.

CHIEFS 24, SEAHAWKS 20: Kansas City (7-3) stopped Seattle (6-4) on fourth down three times in the fourth quarter, holding on for a tense win at home.

Jamaal Charles ran for 159 yards and two touchdowns and Knile Davis also ran for a score as the Chiefs won their fifth straight game and moved into a tie for first in the AFC West.

TEXANS 23, BROWNS 7: J.J. Watt caught a 2-yard touchdown pass from Ryan Mallett and dominated on defense as Houston (5-5) won at Cleveland (6-4).

Mallett threw a pair of TD passes and finished with 211 yards in his first career start. The Texans played without star running back Arian Foster because of a groin injury, but rookie Alfred Blue gained 156 yards on a franchise-record 36 carries.

CARDINALS 14, LIONS 6: Drew Stanton threw touchdown passes to Michael Floyd on Arizona’s first two possessions, and Arizona (9-1) beat visiting Detroit (7-3) for its sixth straight win.

Stanton, starting after Carson Palmer was lost for the season with a knee injury, threw TD passes of 42 and 12 yards.

49ERS 16, GIANTS 10: San Francisco rookie linebacker Chris Borland intercepted a fourth-down pass by Eli Manning at the 49ers 2 with 4:43 to play, capping a goal-line stand as the visiting 49ers (6-4) sent error-plagued New York (3-7) to its fifth straight loss.

Borland had two of the 49ers’ five interceptions, Colin Kaepernick threw a 48-yard touchdown pass to Michael Crabtree and Phil Dawson kicked three first-half field goals.

BENGALS 27, SAINTS 10: Andy Dalton rebounded from one of the worst outings of his career by passing for three touchdowns, and Cincinnati (6-3-1) handed New Orleans (4-6) its second straight home loss.

BEARS 21, VIKINGS 13: Jay Cutler threw for 330 yards and three touchdowns, and Chicago (4-6) won for just the second time in seven games, beating Minnesota (4-6) at home.

FALCONS 19, PANTHERS 17: Matt Ryan threw for 268 yards and a touchdown, Matt Bryant added four field goals and Atlanta (4-6) moved into a tie for first in the NFC South with a win at Carolina (3-6-1).

Bryant’s 44-yard field goal with 2:08 left put Atlanta ahead for good. Carolina’s Graham Gano missed a 46-yard field goal try with 1:27 remaining and had a 63-yarder blocked as time expired.

CHARGERS 13, RAIDERS 6: Philip Rivers threw a 22-yard touchdown pass to Malcom Floyd on the third play from scrimmage, and San Diego (6-4) held on for a lackluster victory against visiting Oakland (0-10), extending the Raiders’ losing streak to 16.

BUCCANEERS 27, WASHINGTON 7: Mike Evans caught seven passes for 209 yards and scored two touchdowns to help visiting Tampa Bay (2-8) end a five-game losing streak.

Evans, a rookie, became the youngest player in NFL history with a 200-yard receiving game.

Tampa Bay’s defense forced three turnovers and sacked Robert Griffin III six times as Washington dropped to 3-7.