CHAPEL HILL, N.C. — Malcolm Brogdon scored 17 points and No. 3 Virginia’s defense locked down in the second half to beat No. 12 North Carolina 75-64 on Monday night.

Justin Anderson added 16 for the Cavaliers (20-1, 8-1 Atlantic Coast Conference), who responded to their first loss of the season by blowing open a tight game at halftime for an impressive road win.

Coming off Saturday’s loss to Duke in one of the program’s biggest home games in years, Virginia erased a 33-32 halftime deficit by shooting 50 percent while holding the Tar Heels (17-6, 7-3) completely in check.

POLL: Kentucky is a unanimous No. 1 again in The Associated Press’ Top 25 poll.

The Wildcats are the only undefeated team in Division I following Virginia’s loss to No. 4 Duke last week.

Gonzaga moved up to No. 2 after two easy victories. Virginia dropped to No. 3 and is one spot ahead of Duke despite losing to the Blue Devils.

Wisconsin is No. 5, with Arizona, Villanova, Notre Dame, Kansas and Louisville rounding out the top 10.

KENTUCKY: Coach John Calipari says forward Trey Lyles could miss a second consecutive game for the top-ranked Wildcats because of an undisclosed illness.

During Monday’s Southeastern Conference coaches’ teleconference, he said he doesn’t believe the 6-foot-10 freshman will play Tuesday night against Georgia (14-5, 5-2) and could be out longer.

Lyles is averaging 7.5 points and 5.3 rebounds in 20 games for Kentucky (21-0, 8-0).

WOMEN

(15) DUKE 66: (8) LOUISVILLE 58: Azura Stevens scored 17 points as the Blue Devils beat the Cardinals at Durham, North Carolina.

Elizabeth Williams had 11 points and blocked five shots, while Oderah Chidom added 14 points to help the Blue Devils (16-6, 7-2 Atlantic Coast Conference) win their third straight.

POLL: South Carolina remains No. 1 in The Associated Press poll for the 11th straight week. The Gamecocks stayed perfect at 21-0 after winning all three of their games this past week by an average of nearly 22 points.

South Carolina is followed by UConn, Baylor, Notre Dame and Maryland. Tennessee, Oregon State, Louisville, Florida State and Arizona State to round out the first 10.