EAST RUTHERFORD, N.J.

The winless New York Giants are going to be without offensive catalyst Odell Beckham Jr. for the rest of the season.

Veteran wide receiver Brandon Marshall’s season is over, too.

The Giants announced Monday that Beckham will have surgery for his broken left ankle later this week, and his season officially ended when he was put on injured reserve later in the day along with fellow receiver Dwayne Harris.

“It’s a sad situation,” coach Ben McAdoo said.

Marshall, signed in the offseason to give Eli Manning another reliable target opposite Beckham, announced on Instagram late Monday that he will have season-ending surgery. Marshall left Sunday’s game with an ankle injury.

The 24-year-old Beckham was hurt late in the fourth quarter of Sunday’s 27-22 loss to Los Angeles when Chargers cornerback Casey Hayward fell on his ankle and pinned it to the turf.

Beckham was the last of four Giants’ receivers knocked out of the game.

Harris, who also returns punts and kickoffs, will have surgery Tuesday for a broken foot. He was hurt in the third quarter.

Marshall and Sterling Shepard were hurt on the same series in the second quarter after falls trying to catch passes.

Shepard is listed as day to day.

The Giants re-signed Tavarres King and signed Travis Rudolph off their practice squad to help wide receiver Roger Lewis Jr. for Sunday’s game in Denver.

The Giants also signed receiver Darius Powe to replace Rudolph on the practice squad.

Watt and Mercilus

As the Houston Texans face another long stretch without superstar J.J. Watt, they know the rest of their defense will have to step up to make up for his absence after he and linebacker Whitney Mercilus both suffered season-ending injuries on Sunday night.

“These guys that are there, they’re going to have to step in and … it’s going to be multiple guys,” coach Bill O’Brien said.

“You don’t replace J.J. Watt or Whitney Mercilus with one guy. That’s just ridiculous. It’s going to be a lot of different guys that are going to chip in to help and I think the coaching staff needs to do a great job, too.”

O’Brien confirmed that both were season-ending injuries on Monday, a day after Watt broke his left leg and Mercilus, an outside linebacker, tore a pectoral muscle in a 42-34 loss to the Kansas City Chiefs.

Watt sustained a tibial plateau fracture to end his season early for the second straight year. The three-time Defensive Player of the Year returned in 2017 after missing the last 13 games of last season following his second back surgery.

The defensive end played every game in his first five seasons in the NFL before his injury last year.

Mercilus, who is in his sixth season, started each game this season and had 10 tackles and a sack.

Jadeveon Clowney, who was the top overall pick in the 2014 draft, has grown into a leadership role on this team and knows he’ll have to help the unit figure out a way to deal with the losses as the Texans prepare to host the Browns on Sunday.

“It hurts, a big blow to the team,” Clowney said. “A lot of our game plan was around them two. So we’ve got to find a way to regroup because we’ve got a lot of season left.”

The loss of Mercilus is the latest setback to Houston’s linebackers after veteran middle linebacker Brian Cushing was suspended for 10 games on Sept. 13 for violating the league’s policy on performance-enhancing substances.

With Mercilus out, the Texans will look to Brennan Scarlett to fill in.