LOUISVILLE, Ky. — A.J. Alix made a go-ahead 3-pointer with 1:04 remaining and Nicole Ekhomu added a free throw with 7.8 seconds left Sunday, helping No. 12 Florida State hand No. 2 Louisville its first loss of the season, 50-49.

The Seminoles (18-2, 6-1 Atlantic Coast) trailed 22-9 after the first quarter before rallying, taking their first lead at 37-36 in the third quarter. They won despite shooting 28 percent overall.

Arica Carter’s 3-pointer put Louisville (20-1, 6-1) ahead with 1:54 to go. Alix answered from long range, then Ekhomu made the second of two from the line.

Louisville missed one shot and committed two turnovers in the final 30 seconds before Myisha Hines-Allen hit a layup to end it.

(1) CONNECTICUT 113, TEMPLE 57: Kia Nurse scored 24 points and freshman Megan Walker added a career-best 22 to help UConn (18-0, 7-0 American Athletic) rout Temple (9-9, 1-5) at Philadelphia.

(3) MISSISSIPPI STATE 71, (6) TENNESSEE 52: Victoria Vivians had 24 points and nine rebounds as Mississippi State (20-0, 6-0 Southeastern) defeated Tennessee (16-3, 4-2) to match its best start in school history.

(5) NOTRE DAME 90, CLEMSON 37: Arike Ogunbowale and Jackie Young each scored 23 points for Notre Dame (18-2, 6-1 Atlantic Coast), which shot 62 percent to rout Clemson (11-9, 1-6) at South Bend, Indiana.

(10) SOUTH CAROLINA 81, KENTUCKY 64: A’ja Wilson scored 26 points after missing two games because of an ankle injury, leading South Carolina (16-3, 5-2 Southeastern) over Kentucky (9-11, 1-5) at Lexington, Kentucky.

(11) MISSOURI 88, ARKANSAS 54: Sophie Cunningham scored 22 points to lead five players in double figures for Missouri (17-2, 5-1 Southeastern) against Arkansas (11-9, 2-5) at Columbia, Missouri.

(13) UCLA 64, STANFORD 53: Jordin Canada had 21 points and five assists, and Monique Billings scored 18 points and grabbed eight rebounds to help UCLA (15-4, 6-2 Pac-12) beat Stanford (12-8, 6-2) at Los Angeles.

NORTH CAROLINA 92, (15) DUKE 86: Paris Kea scored a career-high 36 points, including a 3-pointer with 1.8 seconds left that sent the game into overtime, and North Carolina (14-6, 4-3 Atlantic Coast) won at Chapel Hill, North Carolina, to end a seven-game losing streak against Duke (15-5, 4-3).

MINNESOTA 77, (20) IOWA 72: Kenisha Bell scored 21 points, Carlie Wagner added 15, combining for six free throws in the final 25 seconds at Minneapolis, and Minnesota (16-5, 3-3 Big Ten) handed Iowa (15-5, 3-4) its third straight loss.

(21) CALIFORNIA 62, SOUTHERN CAL 59: Kristine Anigwe scored 20 points, Asha Thomas converted the go-ahead three-point play with 1:29 to play as California (14-5, 5-3 Pac-12)edged USC (13-6, 3-5) at Los Angeles.

(22) ARIZONA STATE 73, COLORADO 59: Kianna Ibis scored 24 points, Courtney Ekmark added 16 and Arizona State (14-6, 5-3 Pac-12) beat Colorado (11-8, 2-6) at Tempe, Arizona, for its eighth straight win in the series.

NEBRASKA 52, (25) RUTGERS 42: Kate Cain scored 14 points and grabbed eight rebounds, and Jasmine Cincore added 11 and seven to help Nebraska (14-6, 5-2 Big Ten) beat Rutgers (17-5, 3-2) at Piscataway, New Jersey.

BOWDOIN 102, UM-PRESQUE ISLE 29: The third-ranked Polar Bears (18-0) scored the first 27 points and defeated the Owls (2-12) at Brunswick.

Abby Kelly scored 16 points in 15 minutes for Bowdoin, which led 30-2 after the first quarter and 56-14 at halftime of the nonconference game.

COMMUNITY COLLEGE OF RHODE ISLAND 68, SOUTHERN MAINE CC 47: Jada Littlejohn scored 27 points as the Knights (13-9) beat the Seawolves (14-6) in a nonconference game at Warwick, Rhode Island.

MEN’S BASKETBALL

(2) VIRGINIA 59, WAKE FOREST 49: Kyle Guy scored 17 points and Virginia (18-1, 7-0 Atlantic Coast) beat Wake Forest (8-11, 1-6) at Winston-Salem, North Carolina, for its 10th straight win.

(23) MICHIGAN 62, RUTGERS 47: Moe Wagner scored 16 points and Duncan Robinson added 12 to lift Michigan (17-5, 6-3 Big Ten) to a win over Rutgers (12-9, 2-6) at Ann Arbor, Michigan.

(25) MIAMI 86, NORTH CAROLINA STATE 81: Bruce Brown Jr. scored 19 points and Miami (14-4, 3-3 Atlantic Coast)shot 58 percent to hold off North Carolina State (13-7, 3-4) at Raleigh, North Carolina.