NEW YORK — Luis Severino struck out 11 in seven overpowering innings, beating longtime Yankees nemesis Dallas Keuchel for the second time this year as New York topped the Houston Astros 5-3 on Wednesday night.

Gary Sanchez snapped an 0-for-19 slump with a two-run single and the Yankees took 2 of 3 from the reigning World Series champions this week to win the season series 5-2. Houston defeated New York in the 2017 AL Championship Series, with the home team winning all seven games.

If these budding rivals meet again this year, it will be in October.

Severino (8-1) allowed four hits, including Max Stassi’s two-run homer, and walked one in winning his sixth consecutive decision. Severino, who hasn’t lost since April 10 at Boston, threw a five-hitter with 10 strikeouts for his first career complete game in a 4-0 victory over Keuchel at Houston on May 2.

David Robertson struck out two in a scoreless eighth and Aroldis Chapman got three outs for his 12th save in 13 chances. Stassi hit an RBI double with two outs in the ninth before Chapman fanned George Springer to end it.

After dominating the Yankees for years, Keuchel (3-7) dropped his third straight start against them – including the playoffs. The left-hander gave up four runs and seven hits in five-plus innings.

Keuchel entered 6-4 with a 1.82 ERA and two complete games in 10 outings against New York, including three postseason starts.

He walked two batters in the first inning, and center fielder Jake Marisnick made a diving catch on a sacrifice fly by Giancarlo Stanton.

Sanchez rolled a two-run single through an open right side with two outs in the fifth to put the Yankees ahead 3-2.

Gleyber Torres doubled to start the sixth and scored from third on Didi Gregorius’ single through a drawn-in infield that chased Keuchel. Aaron Hicks looped an RBI double off Collin McHugh later in the inning that got past a diving Marwin Gonzalez in left field.

INDIANS 9, WHITE SOX 1: Corey Kluber pitched six shutout innings and reached eight victories before any AL pitcher as host Cleveland won its fifth straight.

Yolmer Sanchez homered leading off the ninth as the White Sox avoided a shutout.

Kluber is tough to deal with under normal circumstances, but with a big lead and pitching at home, he’s nearly unbeatable. He is 5-0 with a 1.26 ERA at Progressive Field, and he didn’t walk a batter for the fourth straight start.

NATIONAL LEAGUE

REDS 7, DIAMONDBACKS 4: Adam Duvall’s grand slam erased an early four-run deficit, and Cincinnati rallied to win at Phoenix.

BREWERS 3, CARDINALS 2: Orlando Arcia hit a go-ahead single in a two-run seventh to lead Milwaukee over visiting St. Louis.

Milwaukee, at 19-8, set a team record for wins in May.

PIRATES 2, CUBS 1: Joe Musgrove pitched seven strong innings and his hard slide led to both teams emptying their benches in another tense moment in the series between NL Central rivals, leading Pittsburgh to a win at home.

METS 4, BRAVES 1: Brandon Nimmo and Adrian Gonzalez each drove in two runs, Jason Vargas pitched five scoreless innings and New York won at Atlanta.

INTERLEAGUE

NATIONALS 2, ORIOLES 0: Max Scherzer pitched eight innings of two-hit ball to earn his eighth consecutive victory, Bryce Harper hit his 18th home run and Washington won at Baltimore.

NOTES

TWINS: The Twins placed outfielder Byron Buxton on the 10-day disabled list with a left big toe fracture.

INDIANS: Reliever Andrew Miller can start a throwing program as he battles inflammation in his right knee.

Miller, who is on the disabled list for the third time in the past year because of soreness in his knee, visited a specialist in New York on Tuesday. The club said Dr. David Altchek confirmed a previous diagnosis and the left-hander can “begin a gradual progression back to mound activity.”

CUBS: Right-hander Yu Darvish has inflammation in his right triceps but no structural damage, and could start a throwing program as soon as the weekend.