NEW YORK — Aaron Judge hit a mammoth three-run drive in the ninth inning for his first walk-off home run in the major leagues to give the New York Yankees a 6-5 comeback victory over the Toronto Blue Jays on Tuesday night.

Giancarlo Stanton tied it with a modest three-run shot in the sixth, and the Yankees rallied for their 14th victory in 16 games after three Toronto ejections left the angry Blue Jays seeing red.

New York overcame a shaky start from Luis Severino and improved to 21-8, the best record in the majors.

George Springer launched a leadoff homer for Toronto, and Lourdes Gurriel Jr. hit a tie-breaking double in the eighth that helped the Blue Jays take a 5-3 lead.

No. 9 batter Jose Trevino and DJ LeMahieu drew consecutive one-out walks in the ninth from Jordan Romano (1-2) before Judge sent a hanging 1-2 slider 450 feet into the second deck in left field. The big slugger did a little dance as he approached the plate and was swarmed by excited teammates.

Judge and Stanton have homered in the same game 20 times, including the postseason, and the Yankees have won 19 of those games.

It was the second blown save in 14 chances this season for Romano, who began the night leading the majors in saves.

Wandy Peralta (1-0) pitched a hitless ninth for the win.

Santiago Espinal had an early two-run double — originally ruled a home run — as Toronto quickly built a 3-0 lead against Severino, who started on eight days’ rest.

Yusei Kikuchi pitched five hitless innings before Stanton tied the score in the sixth with a three-run homer off reliever Yimi García that cleared Yankee Stadium’s short right-field porch by just a few rows.

That’s when the fireworks really started.

García hit the next batter, Josh Donaldson, just around the left elbow pad with a 94 mph fastball on an 0-1 count.

Players on the New York bench didn’t like it, but Donaldson calmly went to first base and the umpires convened on the infield grass.

After a long discussion, crew chief Alfonso Marquez ejected Garcia, enraging the pitcher and several Blue Jays who came spilling out of the dugout. In the heated exchange, Marquez then tossed pitching coach Pete Walker as well.

And when Yankees reliever Jonathan Loáisiga brushed back Bo Bichette with a 97 mph fastball in the seventh, plate umpire Lance Barrett heard something from the Blue Jays’ bench and ejected flabbergasted manager Charlie Montoyo.

Toronto regained its composure and put together a two-run rally in the eighth. Vladimir Guerrero Jr. drew a leadoff walk from Loáisiga and raced all the way home from first with a headfirst slide on Gurriel’s line-drive double to left field off Chad Green.

Gurriel advanced to third on the throw home and scored on Alejandro Kirk’s sacrifice fly.

Toronto has lost three straight and 6 of 8.

ASTROS 5, TWINS 0: Justin Verlander missed out on his fourth no-hitter by five outs but still faced the minimum through eight innings, and visiting Houston won its eighth straight.

Twins third baseman Gio Urshela singled to right field with one out in the eighth to end Verlander’s bid. The 39-year-old right-hander, in his first season back from Tommy John surgery, finished the eighth by getting Royce Lewis to ground into a double play.

Verlander was vying to tie Sandy Koufax for second on the career no-hitter list. Nolan Ryan holds the record with seven.

RANGERS 6, ROYALS 4: Corey Seager snapped an 0-for-16 slump with two home runs, Martin Perez pitched 6 1/3 solid innings and Texas opened a nine-game homestand by beating Kansas City.

WHITE SOX 4, GUARDIANS 1: Gavin Sheets homered in his second straight game, Tim Anderson had three hits and 2 RBI and Chicago won at home.

TIGERS-ATHLETICS SPLIT: Tarik Skubal was planning to head to the mound for the day’s first pitch. Then he realized the Detroit Tigers were the visiting team at Comerica Park and Oakland’s Frankie Montas would be on the rubber.

“Thank God someone mentioned it before the game, because I almost ran out there for the top of the first inning,” Skubal said. “Montas and I would have both been on the mound. It was weird, but that’s baseball.”

Skubal led the Tigers to a 6-0 win in the opener of a unique doubleheader caused by Major League Baseball’s lockout. With the Athletics as the visiting team in the second game, 25-year-old Adrian Martinez (1-0) pitched 5 1/3 scoreless innings to win his major league debut, a 4-1 Oakland victory.

In a matchup of last-place teams, Detroit ended a 27-inning scoreless streak in the opener. Oakland (12-19) then won for the second time in 12 games and sent the Tigers (9-21) to their seventh loss in eight games.

Miguel Cabrera singled in the ninth inning of the second game, tying Wade Boggs for 30th with 3,010 hits.

Skubal (2-2) allowed three hits in seven innings, struck out five and walked three. Jonathan Schoop homered and scored twice on a day he raised his batting average from .139 to .157.

Under MLB’s original schedule announced last year, Detroit was to have played three games at Oakland from April 4-6 in its second series of the season. But the first week was postponed by the lockout, and MLB rescheduled one of the games as part of a doubleheader at Comerica Park while keeping Oakland as the home team. The other games are to be played as a doubleheader at the Oakland Coliseum on July 21, what was to have been an off-day during the All-Star break.

Detroit wore its white home uniforms despite batting first, while the A’s wore green tops and gray pants. The Tigers reverted to the home team in the second game.

NATIONAL LEAGUE

DODGERS 11, PIRATES 1: Justin Turner hit three of the Los Angeles Dodgers’ eight doubles and finished with four hits and four RBI in a win at Pittsburgh.

The Dodgers hadn’t hit eight doubles in a game since moving to Los Angeles from Brooklyn in 1958. The franchise record is nine.

METS 4, NATIONALS 2: James McCann’s sacrifice fly drove in the go-ahead run during a three-run sixth inning, and Carlos Carrasco nearly got to the seventh again, helping the Mets win at Washington.

BREWERS 5, REDS 4: Josh Hader reached 500 career strikeouts, Luis Urias hit tying home run and made a clutch catch and visiting ended Cincinnati’s two-game winning streak.

Jace Peterson broke a 1-1 tie in the sixth with the first of his two doubles for the NL Central-leading Brewers, who ended a three-game losing streak.

INTERLEAGUE

ORIOLES 5, CARDINALS 3: Cedric Mullins and Tyler Nevin each homered and Kyle Bradish struck out 11 over seven strong innings, leading Baltimore to a win at St, Louis.

Mullins also added three singles and a stolen base in a 4-for-5 night. Anthony Santander added three hits, including a RBI double for Baltimore.

NOTES

WHITE SOX: Major League Baseball dropped the one-game suspension of shortstop Tim Anderson for giving fans the middle finger during a game on April 20 as part of a settlement with the players’ association.

He agreed to a fine as part of the settlement, which avoided an appeal before MLB special adviser John McHale Jr.

Anderson had three errors in the first two innings of Chicago’s 11-1 loss in the opener of a doubleheader and made the gesture toward a fan while out in the field. MLB senior vice president Michael Hill announced the suspension two days later.

The 28-year-old served a two-game ban on opening weekend for making contact with umpire Tim Timmons during the ninth inning of a game on Sept. 27, a penalty reduced from three games originally assessed by Hill.

TWINS: The Minnesota Twins placed shortstop Carlos Correa on the 10-day injured list with a bruised right middle finger that wasn’t healing fast enough for him to face his former team.

The move, retroactive to last Friday, was made before the Twins began a three-game series against the Houston Astros, for whom Correa played over the past seven seasons. Correa will be eligible for reinstatement to the active roster next Monday, meaning he must sit out at least six more games.

METS: Two-time Cy Young Award winner Jacob deGrom was moved to the 60-day injured list by the New York Mets on Tuesday in a procedural move that does not necessarily indicate any news about his progress in returning from a stress reaction on his right shoulder blade.

DeGrom has not pitched this season and has been expected to be sidelined at least until June. By shifting the right-hander from the 10-day IL, the NL East-leading Mets made room on their 40-man roster for lefty Locke St. John, who was waived by the Chicago Cubs.

Speaking to reporters before Tuesday night’s game at the Washington Nationals, Manager Buck Showalter wouldn’t offer any specifics about where things stand with deGrom. He went on the injured list on Opening Day, April 7, after getting hurt late in spring training.

PADRES: Manager Bob Melvin says he’ll have prostate surgery Wednesday and hopes he misses only part of a forthcoming trip.

Melvin said he doesn’t think he has cancer, “but they won’t know until they get in there.” He was in street clothes during his pregame session with the media before Tuesday night’s game against the Chicago Cubs.

Melvin, who was hired away from Oakland on Nov. 1, said he’s been feeling various symptoms since the team returned from a trip last Wednesday night.

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