
Thirteen-year-old Hayden Murphy of Plainfield, Illinois, is helping researchers determine if the strategy works for Type 1 diabetes, the kind that is usually diagnosed in childhood. If it does, he might be able to avoid the lifetime burdens facing his 5-year-old brother, Weston. They includes countless finger pricks and blood sugar checks, and avoiding playing too hard or eating too little, which both can cause dangerous blood sugar fluctuations.
Hayden Murphy is among more than 400 children and adults participating in U.S. government-funded international research investigating whether experimental insulin capsules can prevent or at least delay Type 1 diabetes. Hospitals in the United States and eight other countries are involved and recruitment is ongoing. To enroll, participants must first get bad news: results of a blood test showing their chances for developing the disease are high.
“When I got the news, I was devastated,” Hayden said. He knows it means his life could change in an instant.
“He has the daily reminders. He sees what his brother goes through,” said the boys’ mom, Myra Murphy.
So now Hayden Murphy swallows a small white capsule daily and has his blood checked periodically for signs of diabetes.
“I hope it doesn’t come to me, and I really didn’t want it to come to him,” Hayden said.
A small, preliminary study by different researchers, published recently in the Journal of the American Medical Association, suggests the approach might work. Children who took insulin pills showed immune system changes that the researchers said might help prevent diabetes. The study was too small and didn’t last long enough to know for sure.
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