COLUMBUS, Ohio (AP) — Draymond Green scored 16 points with 13 rebounds and set up Keith Appling’s crucial 3- pointer with 1:34 left, giving top-seeded Michigan State a 65-61 win over Saint Louis on Sunday and sending the Spartans to the round of 16 in the NCAA tournament.

Michigan State will play No. 4 seed Louisville in the West Regional semifinals Thursday in Phoenix.

Kwamain Mitchell scored 13 and Brian Conklin 11 for Saint Louis, back in the tournament for the first time since 2000.

No. 7 Florida 84, No. 15 Norfolk State 50

OMAHA, Neb. (AP) — Kenny Boynton scored 20 points and Florida routed Norfolk State to reach the regional semifinals of the NCAA tournament for the second straight year.

The Gators ( 25- 10) made it to the regional semifinals for the sixth time in 12 NCAA tournament appearances under coach Billy Donovan. They will play No. 3 seed Marquette on Thursday in Phoenix after their second straight runaway win.

MIDWEST REGIONAL

No. 1 North Carolina 87, No. 8 Creighton 73

GREENSBORO, N. C. ( AP) — John Henson proved he’s healthy enough to help North Carolina’s latest push for the Final Four. It remains to be seen if Kendall Marshall will be able to help the Tar Heels.

Henson had 13 points, 10 rebounds and four blocks in his return from a wrist injury, but Marshall broke a bone in his right wrist during the second half of North Carolina’s third-round victory over Creighton.

Doug McDermott scored 20 points for the Bluejays (29-6), who shot 41 percent and couldn’t keep up with the hot-shooting Tar Heels.

No. 13 Ohio 62, No. 12 South Florida 56

NASHVILLE, Tenn. (AP) — Walter Offutt scored 21 points, D.J. Cooper had 19 and Ohio beat South Florida to advance to the regional semifinals.

The Bobcats (29-7) will play No. 1 seed North Carolina in their second trip to the round of 16.

Victor Rudd Jr. and Anthony Collins both scored 13 points for the Bulls (22-14).

No. 2 Kansas 63, No. 10 Purdue 60

OMAHA, Neb. (AP) — Elijah Johnson scored 18 points, including the go-ahead basket off a steal in the final minute, and Kansas rallied to beat Robbie Hummel and Purdue after trailing almost the entire way.

Thomas Robinson had 11 points and 13 rebounds for the Jayhawks (29-6), who were down by 10 in the second half but still managed to advance to St. Louis. They’ll play No. 11 seed North Carolina State on Friday in the Midwest Regional semifinals.

Hummel finished with 26 points and nine rebounds to lead the Boilermakers (22-13).

No. 11 No. Car. St. 66, No. 3 Georgetown 63

COLUMBUS, Ohio (AP) — Lorenzo Brown hit three free throws in the final 10.6 seconds and North Carolina State conjured up its glorious tradition by upsetting Georgetown.

C. J. Williams, Scott Wood and C. J. Leslie each had 14 points, and Brown added 12 for the Wolfpack, who earned their first trip to the round of 16 since 2005.

Hollis Thompson led the Hoyas with 23 points.

SOUTH REGIONAL

No. 10 Xavier 70, No. 15 Lehigh 58

GREENSBORO, N.C. (AP) — Senior center Kenny Frease scored a careerhigh 25 points to go with 12 rebounds and Xavier knocked off upset-minded Lehigh to reach the round of 16 for the fourth time in five years.

The Musketeers held C.J. McCollum, the nation’s fifth-leading scorer, to 14 points on 5-of-22 shooting and overcame a 15-point first-half deficit. Mackey McKnight had 20 points for Lehigh (27-7), which tied a Patriot League record for wins in a season.

EAST REGIONAL

No. 6 Cincinnati 62, No. 3 Florida State 56

NASHVILLE, Tenn. ( AP) — Dion Dixon stole the ball and dunked to put Cincinnati ahead for good with 1:32 left and the Bearcats edged Florida State to reach their first regional semifinal in the NCAA tournament since 2001.

Sean Kilpatrick scored 18 points and Dixon finished with 15 for Cincinnati. Yancy Gates had 10, and JaQuon Parker grabbed 11 rebounds.

Florida State (25-10) had its six-game winning streak snapped. Luke Loucks led Florida State with 14 points.