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SAN FRANCISCO (AP) — Matt Cain pitched the 22nd perfect game in major league history and first for the Giants, striking out a career-high 14 and getting help from two spectacular catches to beat the Houston Astros 10-0 on Wednesday night.

Cain’s 125-pitch masterpiece for San Francisco featured a pair of great plays by his corner outfielders. He got pinch-hitter Jason Castro on a grounder to third for his 27th and final out with the sellout crowd of 42,298 roaring.

It was the fifth no-hitter in the majors already this year and second perfect game. At a ballpark where Barry Bonds made home run history, Cain produced the signature moment for pitchers.

Left fielder Melky Cabrera chased down Chris Snyder’s one-out flyball in the sixth, scurrying back to make a leaping catch at the wall. Cain raised both arms and slapped his glove in delight when Cabrera made the play.

Then, right fielder Gregor Blanco ran into deep right-center to make a diving catch on the warning track and rob Jordan Schafer for the first out of the seventh. The 27-year-old pitcher hugged Blanco in the dugout after the inning.



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