CHICAGO (AP) — Alex Rodriguez blooped a single into left field in his first at-bat of the season, hours after being hit with a long suspension.

It was a nice start for the embattled slugger, but that was it. The finish belonged to the Chicago White Sox.

Rodriguez went 1 for 4 in his first game for New York, but the White Sox beat the struggling Yankees 8- 1 on Monday night to snap a 10-game losing streak.

Rodriguez was suspended through 2014 by Major League Baseball in the Biogenesis case, a punishment he is appealing.

That clearly was the biggest story on a day when New York’s Derek Jeter went back on the disabled list because of a strained right calf and Andy Pettitte (7-9) got knocked out early. Alex Rios drove in four runs, Alexei Ramirez added four hits and Jose Quintana (6- 3) pitched into the seventh for the White Sox.

Tigers 4, Indians 2

CLEVELAND (AP) — Alex Avila’s three-run homer in the ninth inning off closer Chris Perez rallied Detroit to its ninth straight win.

The Tigers were three outs away from having their lead in the AL Central cut to two games before their comeback against Perez (4-2), who had converted 11 consecutive save opportunities.

After Victor Martinez’s RBI single made it 2-1, Perez walked Andy Dirks before Avila drove a 1-0 pitch over the wall in left-center for his ninth homer, stunning a Cleveland crowd ready to celebrate the team’s biggest win this season.

Manager Terry Francona had no choice but to relieve the controversial Perez, who sullenly walked to the dugout after not retiring a batter and heard only boos from Indians fans.

It was a demoralizing setback for the Indians, who fell to 3-10 against the Tigers this season and had their home winning streak stopped at 11.

Rangers 5, Angels 2

ANAHEIM, Calif. (AP) — Adrian Beltre homered, Martin Perez pitched into the seventh inning, and Texas beat Los Angeles after losing All-Star outfielder Nelson Cruz to a 50-game suspension.

Jurickson Profar had a run-scoring hit for Texas, which has won seven of eight to move within two games of AL West leader Oakland.

After Cruz spoke about his doping suspension in a pregame meeting, the Rangers uniformly stood behind their longtime teammate. David Murphy took over in right field for Cruz, scoring two runs but also misplaying two balls.

Elvis Andrus got credit for a two-run triple in the fifth inning when Angels second baseman Howie Kendrick hyperextended his left knee while failing to catch Andrus’ popup to the outfield.

Royals 13, Twins 0

KANSAS CITY, Mo. (AP) — Jeremy Guthrie pitched a four-hitter and Eric Hosmer drove in a career-high five runs to help Kansas City rout Minnesota.

The Royals, who have won 12 of their past 13 games, scored a season-high 13 runs.

Guthrie (12-7) won his fourth straight start to log his 12th victory, which is a career high. It was his second career shutout and he lowered his ERA to 3.94.

The Royals sent 11 men to the plate in a six-run second inning, which was highlighted by Mike Moustakas and Hosmer stroking two-run singles. Moustakas collected two hits in the inning.

Hosmer hit his 12th home run in the sixth with Jarrod Dyson and Cain aboard.

Moustakas, who had two hits in the second inning, went 4 for 5, matching his career high for hits.

Blue Jays 3, Mariners 1

SEATTLE (AP) — Mark DeRosa’s pinch-hit, two-run single in the eighth inning gave Toronto and R.A. Dickey a victory over Seattle.

Dickey (9-11) went 7.2 innings, allowing one run on eight hits. The knuckleballer struck out five and walked two to earn his first win since July 1. Casey Janssen worked the ninth for his 20th save in 22 opportunities.

Hisashi Iwakuma (10-5), who pitched 7.1 innings, took the loss. He allowed two runs on four hits, striking out two and walked a season-high three.

Justin Smoak hit his 11th home run in the seventh to give the Mariners a 1-0 lead.

Dodgers 3, Cardinals 2

ST. LOUIS (AP) — Zack Greinke pitched into the seventh inning and raised his batting average to .405 with an RBI single, helping the Los Angeles Dodgers win their 15th straight on the road with a victory over the St. Louis Cardinals.

Nick Punto was productive subbing for injured shortstop Hanley Ramirez and the Dodgers got an RBI apiece from Andre Ethier and A.J. Ellis while matching the Cincinnati Reds’ 15-game run in 1957. They’re two wins shy of the NL record set by the 1916 New York Giants.

Greinke (9-3) allowed two runs in 6.1 innings for his 100th career victory, allowing two hits in the third, fourth and fifth but no runs. Paco Rodriguez earned his second career save with a perfect ninth.

Braves 3, Nationals 2

WASHINGTON (AP) — Justin Upton led off the eighth inning with a tiebreaking homer, and the NL East-leading Braves extended their winning streak to a season-high 11 games by beating the fading Nationals.

Freddie Freeman drove in Atlanta’s first two runs with a pair of singles in the third and fifth. Reliever David Carpenter (3-0) earned the win by retiring all five batters he faced.

Upton’s 20th homer came on a 3-2 pitch from Tyler Clippard (6-2), who replaced Stephen Strasburg to begin the eighth.

The Nationals again failed to provide much run support for Strasburg, who struck out nine in seven innings, allowing two runs and five hits. The last five times he’s allowed two earned runs or fewer, Washington lost.

Giants 4, Brewers 2

SAN FRANCISCO (AP) — Pinch hitter Jeff Francoeur’s broken-bat single in the bottom of the eighth inning drove in the go-ahead run in the Giants’ victory over the Brewers.

Brandon Belt had three hits for the Giants, who won for the fourth time in six games. Hunter Pence walked three times and stole two bases.