ALBANY, N.Y. — Dominique Mayfield makes $8.25 an hour washing dishes and busing tables at a Syracuse brewpub. Shantel Walker makes $8.50 an hour at her pizzeria in New York City, where the rent is more than double what it is in Syracuse. Two very different cities, but nearly the same wage.

The economic differences between America’s big cities and elsewhere have prompted leaders in Seattle, New York City, Chicago, San Francisco, Oklahoma City and other cities to push to raise the minimum wage within their borders.

The efforts are running into opposition from state lawmakers from both parties and business groups who say a patchwork of minimum wages could lead to a confusing and unequal business climate in which labor costs would vary dramatically from city to city.

The minimum wage has emerged as perhaps the top issue of a newly emboldened, urban liberal movement that in many places is led not by governors or state lawmakers, but by local leaders backed by organized fast-food workers. After years of grappling with state and federal budget cuts, mayors and city councils are fighting back against state and federal officials who they say don’t understand the income inequality of 21st-century American cities.

“So many people have been pushed out of this city,” said Seattle City Councilman Nick Licata, who successfully campaigned to raise the city’s wage to $15, more than $5 higher than the state wage. “Local politicians don’t have the luxury of not doing something. The state and federal governments, they’ve been AWOL.”

The fight to raise minimum wages has lawmakers in many states on the defensive, arguing that higher wages will lead to reductions in hours and jobs for low-income workers – and retail price increases that are likely to hit them hardest. The business-backed American Legislative Exchange Council argues that local minimum wages could lead to a race to the bottom, where businesses locate in whatever city within a region has the lowest starting wage.

“This is a debate that’s happening around the country, and although it’s well intended, it’s misguided,” said Cara Sullivan, a minimum wage policy expert at ALEC. “In Seattle they raised it to $15, and right across the city line it’s $5 less. It increases the cost of doing business for businesses in that city. You’re creating chaos from one business to the next.”

Members of the city council in Providence, R.I., considered raising the minimum wage from $8 to $15, but only for workers in the city’s large hotels. In response, the Democratic leaders of the Rhode Island General Assembly have moved to block the proposal by taking away cities’ authority to set local minimums.

Oklahoma Gov. Mary Fallin, a Republican, signed legislation in April that prohibits cities from setting their own wage after organized labor groups suggested that Oklahoma City raise its wage from $7.25 an hour – the federal minimum – to $10.10.

B.J. Marsh, a single mother in a suburb of Oklahoma City, says the $7.25 she makes requires her to choose between eating or getting to work. Marsh said her 7-year-old son began living with her father to save on expenses and allow her to work. “I don’t eat because I have to have gas in my car,” she said.