SEATTLE (AP) — Hisashi Iwakuma has become the second Japanese-born pitcher in major league history to throw a no-hitter, leading the Seattle Mariners to a 3-0 victory over the Baltimore Orioles on Wednesday.

Iwakuma struck out seven and walked three in throwing the first no-hitter by an American League pitcher in nearly three years. He joins Hideo Nomo, who threw two no-nos, as the only Japaneseborn pitchers to accomplish the feat.

Iwakuma is the fourth pitcher to throw a no-hitter this season, joining Philadelphia’s Cole Hamels — prior to his trade to Texas — Washington’s Max Scherzer and San Francisco’s Chris Heston.

Dodgers 3, Nationals 0

LOS ANGELES (AP) — Clayton Kershaw tied Sandy Koufax’s franchise record of six straight 200-strikeout seasons while tossing eight scoreless innings, and NL West-leading Los Angeles defeated Washington.

Kershaw (10-6) took a perfect game bid into the sixth inning, when Michael Taylor doubled to deep center field. Kershaw retired the next two batters on grounders to end the inning.

Blue Jays 10, A’s 3

TORONTO (AP) — Toronto surged to the top of the AL East with its 10th straight win, beating Oakland behind a pair of threerun homers from Chris Colabello and Justin Smoak.

The Blue Jays trailed the Yankees by six games on July 31. But after making several bold trades, they have gone on a streak that included a sweep of New York, losing only once since Troy Tulowitzki joined the team to move a half-game up in the division.

Indians 2, Yankees 1

CLEVELAND (AP) — Danny Salazar pitched neatly into the eighth inning, and Cleveland dropped New York out of first place in the AL East.

The Yankees, who have lost five straight, trail surging Toronto by a half-game in the division and fell out of the top spot for the first time since July 2. New York has scored six runs in its losing streak.

Mets 3, Rockies 0

NEW YORK (AP) — Jacob deGrom conceded only two hits and struck out 10 in seven innings, pitching New York past Colorado.

Yoenis Cespedes hit his first home run for the surging Mets, who have won 10 of 12. Juan Uribe stroked an RBI double in the fourth and Michael Cuddyer followed with a run-scoring single on a night when both players reached 1,500 career hits.

Cardinals 4, Pirates 2

ST. LOUIS (AP) — Yadier

Molina tripled in the goahead run in the sixth inning when right fielder Gregory Polanco missed an attempted shoe-top catch and Michael Wacha got his 14th win to tie for the major league high as St. Louis beat Pittsburgh.

The game didn’t live up to the anticipated marquee pitching matchup between Wacha (14-4) and Gerrit Cole (14-6), both of whom were gone by the seventh inning. Seattle’s Felix Hernandez also has 14 wins.

Cubs 3, Brewers 2

CHICAGO (AP) — Miguel Montero homered in the bottom of the 10th inning to give Chicago a victory over Milwaukee for the Cubs’ sixth straight win and 12th in 13 games.

Montero, who allowed a couple wild pitches to get past him in the ninth as the Brewers rallied to tie the score, led off the 10th with a solo blast to left field off Michael Blazek (5-3).

Astros 2, Giants 0

SAN FRANCISCO (AP) — Colby Rasmus homered to lead off the seventh inning to help Scott Feldman earn his first win in more than two months, and Houston held on to beat San Francisco.

Jed Lowrie also homered for the Astros, who stumble back to Minute Maid Park with a slimmer AL West division lead after going 2-7 on their nine-game road trip.

White Sox 3, Angels 2

CHICAGO (AP) — Avisail Garcia’s line-drive double to the wall with one out in the 13th inning drove in Jose Abreu from first base and lifted Chicago to a win over Los Angeles to finish a three-game sweep.

Tigers 7, Royals 4

KANSAS CITY, Mo. (AP) — Ian Kinsler doubled home two runs and Detroit batted around in a four-run eighth inning to defeat Kansas City.

Twins 11, Rangers 1

MINNEAPOLIS (AP) — Aaron Hicks had four of Minnesota’s 17 hits, Miguel Sano homered twice and Mike Pelfrey picked up his first win since June as the Twins routed Texas.

Reds 7, Padres 3

SAN DIEGO (AP) — Rookie Raisel Iglesias pitched six strong innings and Joey Votto scored the go-ahead run on a balk by James Shields and later homered to lead Cincinnati to a victory against San Diego.

Phillies 7, D-Backs 6

PHOENIX (AP) — Cameron Rupp homered and drove in a career-high four runs and Philadelphia avoided a series sweep with a win over Arizona.

Rays 9, Braves 6

ST. PETERSBURG, Fla. (AP) — Curt Casali capped a six-run seventh inning with a two-run homer and Tampa Bay rallied for a victory over Atlanta.

Casali had just one hit in 26 at-bats since consecutive two-homer games against Detroit on July 27-28.

Tampa Bay has won four in a row, including three when trailing 3-0.