SAN FRANCISCO (AP) — Hunter Pence hit a grand slam in the eighth inning, Joe Panik drove in three runs to key San Francisco’s comeback, and the Giants beat the Los Angeles Dodgers 12-6 in their home opener Thursday.

The Dodgers’ 31-inning shutout streak ended in the fifth, one inning shy of the record to begin a season set by the 1963 St. Louis Cardinals.

Chris Heston (1-0) worked the sixth in relief of Jake Peavy for the victory as San Francisco erased a 4-0 deficit. Bruce Bochy bested his former outfielder and now-Dodgers manager Dave Roberts in their first matchup.

In the fifth, Los Angeles finally gave up its first runs of 2016 when the Giants got to Alex Wood (0-1).

Joc Pederson hit a two run homer for the Dodgers.

Yankees 8, Astros 5

NEW YORK (AP) — Mark Teixeira sliced a tiebreaking, three-run homer in the seventh inning and Starlin Castro connected again, sending New York past Houston.

The Yankees took two of three in the season-opening series against the team that beat them in the AL wildcard game last October.

Castro kept up his torrid start with a solo home run and a single off the wall, making him 7 for 12. The former Cubs infielder has eight RBIs, the most by any player in his first three games for the Yankees since the stat became official in 1920, STATS said.

Brian McCann also homered for the Yankees, and Jacoby Ellsbury doubled twice. Alex Rodriguez made it 5-all with his first hit of the season, an RBI single in the fifth.

Marlins 6, Nationals 4

WASHINGTON (AP) — Miami reliever David Phelps entered after a rain delay and shut out Washington for four innings while delivering his first career RBI at the plate, and the Marlins spoiled the Nationals’ sloppy home opener in front of a dwindling crowd.

While Phelps (1-0) replaced Adam Conley following a 1-hour, 25-minute break because of a thunderstorm in the second with the score 3-all, Nationals starter Tanner Roark (0-1) surprisingly remained in the game. Roark allowed four runs — three earned, all in the first — and nine hits in four innings.

Reds 10, Phillies 6

CINCINNATI (AP) — Jay Bruce homered twice and matched a career high with five RBIs, and Cincinnati made a winner of top pitching prospect Robert Stephenson in his major league debut by beating Philadelphia to complete a season opening sweep.

Eugenio Suarez hit his first career grand slam and Bruce connected for a three run shot as the Reds scored eight times in the fourth inning, ruining the big league debut of reliever Daniel Stumpf. Bruce capped the 13-batter outburst with an RBI single. innings in his Phillies debut.

White Sox 6, A’s 1

OAKLAND, Calif. (AP) — Mat Latos gave up one hit over six shutout innings for his first win since last July, Jose Abreu hit a two-run homer and Chicago beat Oakland to give manager Robin Ventura his 300th career win.

Orioles 4, Twins 2

BALTIMORE (AP) — Ubaldo Jimenez pitched seven sharp innings and Baltimore rallied to beat Minnesota for a three-game sweep.

Manny Machado and rookie Joey Rickard homered for the Orioles, who trailed 2-0 in the sixth before coming back against Phil Hughes (0-1).

Cubs 14, D-Backs 6

PHOENIX (AP) — Anthony Rizzo matched his career high with six RBIs and the Chicago Cubs beat the Arizona Diamondbacks, but lost Kyle Schwarber with a sprained ankle in an outfield collision.

Angels 4, Rangers 3

ANAHEIM, Calif. (AP) — Albert Pujols hit a bases loaded single with two outs in the ninth inning to give the Los Angeles Angels their first victory of the season.

Yunel Escobar drove in the Angels’ first two runs with a homer.