BUXTON — River Road was reopened to traffic by 10 a.m. Saturday after a vehicle crashed into a tree.

Crews responded after the single-vehicle accident was reported at 6:30 a.m. Arriving at the scene, emergency crews learned two people had been ejected from the vehicle, while two remained pinned inside, according to Buxton Police Chief Michael Grovo.

A press release about the accident said it appears that the vehicle was traveling south on River Road at a high rate of speed and went off the road near the intersection of Back Nippen Road.

Grovo said LifeFlight helicopters took two of the injured to Maine Medical Center in Portland. The other two were taken by ambulance to Maine Medical Center, he said.

Grovo said the department is not releasing the names of those involved because juveniles were involved and he wanted to ensure that their families had been notified.

Buxton Police are investigating the accident, and Maine State Police are working to reconstruct the crash. It is believed that speed and alcohol were factors in the accident, Grovo said.