BUENOS AIRES, Argentina – Three relatives of Pope Francis died and a fourth was in serious condition Tuesday after their car crashed on a provincial highway in Argentina, the Vatican and local officials said.

The small car carrying a nephew of the pope along with the man’s wife and two young children slammed into the back of a truck, Highway Police Superintendent Jorge Raineri said. The crash killed the wife and children, one 2 years old and the other 8 months.

Emanuel Bergoglio, the 38-year-old son of a brother of Pope Francis, was hospitalized in serious condition, Ignacio Bruno, an assistant director of the hospital in the town of Villa Maria, told Todo Noticias television.