Ohio State running back Master Teague lunges into the end zone for a touchdown Saturday during a 42-35 win over Indiana in Columbus, Ohio. Jay LaPrete/Associated Press

COLUMBUS, Ohio — Master Teague ran for a career-high 169 yards and two touchdowns, Justin Fields accounted for three scores and No. 3 Ohio State held off a comeback bid by Michael Penix Jr., Ty Fryfogle and No. 9 Indiana to win 42-35 on Saturday.

The Hoosiers (4-1) rallied from a four-touchdown deficit in the second half and made it a one-score game with 10:26 left, when Penix and Fryfogle connected on a 56-yard touchdown.

Penix was 27 of 51 for a career-high 491 yards and five touchdown passes.

The Buckeyes (4-0) put up 607 yards and led 35-7 early in the second half, but struggled to contain Penix and Fryfogle, who caught seven passes for 218 yards and three touchdowns.

Fields was 18 of 30 for 300 yards and two touchdowns, but he also threw his first three interceptions of the season and was sacked five times.

Garrett Wilson had seven catches for 169 yards – his fourth straight game of 100-plus yards – and two scores for the Buckeyes.

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The running game helped Ohio State steady maintain control when things were getting dicey.

Penix passed for four touchdowns in the second half but also made a critical error, tossing an interception that Ohio State’s Shaun Wade returned for a touchdown at the end of the third quarter.

(1) ALABAMA 63, KENTUCKY 3: DeVonta Smith caught nine passes for 144 yards and set the Southeastern Conference career record with two more touchdowns as the Crimson Tide (7-0 SEC) routed the outmanned Wildcats (3-5) in Tuscaloosa, Alabama.

Smith broke Amari Cooper’s record with his 32nd touchdown catch, a 10-yarder from Mac Jones in the second quarter. He added an 18-yarder from freshman backup Bryce Young.

(6) FLORIDA 38, VANDERBILT 17: Kyle Trask passed for 383 yards and three touchdowns, and the Gators (6-1, 6-1 Southeastern Conference) rallied from an early deficit to beat the Commodores (0-7, 0-7) in Nashville, Tennessee.

Florida pulled into Vanderbilt Stadium an hour before kickoff already in uniform, hoping to avoid the visitors locker room as a coronavirus precaution. The Commodores opened the game by driving for a touchdown, but Trask helped get Florida on track for its seventh consecutive win in the series.

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Trask, a Heisman Trophy hopeful, completed 26 of 35 passes to nine different receivers. He is the first quarterback in SEC history to throw 30 touchdown passes in seven games.

(7) CINCINNATI 36, CENTRAL FLORIDA 33: Desmond Ridder threw two touchdown passes and ran for two scores as the Bearcats (8-0, 6-0 American Athletic) beat the Knights (5-3, 4-3) in Orlando, Florida.

(8) BYU 66, NORTH ALABAMA 14: Tyler Allgeier ran for a career-high 141 yards and two touchdowns and the Cougars (9-0) routed the overmatched Lions (0-4) in Provo, Utah.

(19) NORTHWESTERN 17, (10) WISCONSIN 7: Peyton Ramsey threw two touchdown passes, and the Wildcats (5-0) beat the visiting Badgers (2-1) to take control of the Big Ten West.

(11) OREGON 38, UCLA 35: Tyler Shough threw for 334 yards and three touchdowns, and the Ducks (3-0) held off the short-handed Bruins (1-2) in Eugene, Oregon.

(13) GEORGIA 31, MISSISSIPPI STATE 24: JT Daniels threw for 401 yards and four touchdowns in his Georgia debut, leading the host Bulldogs (5-2, 5-2 Southeastern Conference) to a win in Athens, Georgia.

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Daniels, a transfer from USC who became the third quarterback to start for Georgia this season, delivered one big play after another, capped by a 40-yard touchdown pass to Kearis Jackson that broke a 24-24 tie with 9:50 remaining. What made it more impressive: Jackson and George Pickens had dropped potential TD passes on back-to-back plays, and a holding penalty left Georgia with third-and-20.

But Jackson slipped behind the secondary in the middle of the field, and Daniels spotted him to finally finish off pesky Mississippi State (2-5, 2-5).

(18) OKLAHOMA 41, (14) OKLAHOMA STATE 13: Spencer Rattler passed for 301 yards and four touchdowns and ran for another score to help the Sooners (6-2, 5-2 Big 12) rout the visiting Cowboys (5-2, 4-2).

(15) COASTAL CAROLINA 34, APPALACHIAN STATE 23: Reese White scored the go-ahead touchdown on a 3-yard run with 2:24 to play, and the host Chants (6-0 Sun Belt) beat the four-time defending Sun Belt champions (6-2) for the first time in seven tries.

(17) IOWA STATE 45, KANSAS STATE 0: Brock Purdy passed for 236 yards and three touchdowns, and the Cyclones (6-2, 6-1 Big 12) cruised to their most-lopsided win over the visiting Wildcats (4-4, 4-3) in 77 years.

NORTH CAROLINA STATE 15, (21) LIBERTY 14: Vi Jones blocked Alex Barbir’s 39-yard field-goal attempt with 1:18 left as the Wolfpack (6-3) beat the Flames (8-1) in Raleigh, North Carolina.

(23) AUBURN 30, TENNESSEE 17: Smoke Monday returned an interception 100 yards for a touchdown, and the Tigers (5-2, 5-2 Southeastern Conference) beat the visiting Volunteers (2-5, 2-5) in their first game in 21 days.

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