NEW YORK — Clay Holmes pitched out of a bases-loaded jam in the eighth inning and the New York Yankees stormed back from four runs down against Max Scherzer to beat the skidding New York Mets 7-6 in their wild Subway Series opener Tuesday night at Citi Field.

Giancarlo Stanton and DJ LeMahieu homered off Scherzer, and pinch-hitter Josh Donaldson drove in the tie-breaking run with a sacrifice fly in the sixth after Brandon Nimmo misplayed a ball in center field.

Before the seventh, reliever Drew Smith became the second Mets pitcher ejected this season for using an illegal foreign substance.

Nimmo hit his eighth career leadoff homer and Jeff McNeil had a two-run single for the Mets (31-36), who have lost 9 of 10. They opened a 5-1 lead in the third with the help of two second-inning balks by struggling Yankees starter Luis Severino, only to see Scherzer give up five runs and six hits in the fourth.

LeMahieu’s two-run homer trimmed it to 5-3, slumping rookie Anthony Volpe had an RBI double and Jake Bauers’ two-run bloop single over a drawn-in infield chased Scherzer and gave the Yankees a 6-5 lead.

The three-time Cy Young Award winner was booed by Mets fans in the sellout crowd of 43,707 who showed up to see the first meeting between the teams this season — missing injured sluggers Aaron Judge and Pete Alonso.

Luis Guillorme’s two-out RBI single tied it in the fifth, ending Severino’s night.

The Mets loaded the bases with one out in the eighth. Holmes entered and struck out cleanup batter Francisco Lindor with a sinker in a seven-pitch at-bat and Starling Marte on a slider in an eight-pitch encounter to preserve the one-run lead.

Michael King worked a 1-2-3 ninth for his fourth save. Ron Marinaccio (3-3) pitched a scoreless inning for the win.

TWINS 7, BREWERS 5: Carlos Correa hit a two-run homer to cap a four-run ninth inning off closer Devin Williams, giving Minnesota a win at home.

Correa crushed a 1-1 change-up from Williams (3-1) into the left-field seats, dropping his bat as he turned to his dugout and tapped his wrist to signal it’s his time, like he did for Houston in the 2021 postseason.

REDS 5, ROYALS 4: The Reds batted through the lineup during a five-run second inning, and Brandon Williamson did just enough to earn his first big league win as visiting Cincinnati held off struggling Kansas City.

ASTROS 6, NATIONALS 1: Mauricio Dubón, Kyle Tucker, Martín Maldonado and Chas McCormick each hit solo homers to back a solid start by rookie Hunter Brown and lead Houston over visiting Washington.

Brown (6-3) scattered four hits across seven scoreless innings after losing two in a row.

It was Washington’s first visit to Houston since the Nationals won their only championship by beating the Astros 6-2 in Game 7 of the 2019 World Series.

AMERICAN LEAGUE

ANGELS 7, RANGERS 3: Hunter Renfroe’s two-run home run capped a three-run sixth inning and visiting Los Angeles beat AL West-leading Texas.

Renfroe’s homer helped spoil the major league debut of Owen White (0-1), who was recalled from Double-A Frisco earlier in the day. White entered with one out in the fifth inning and gave up three runs on four hits with two strikeouts and one walk.

The Angels have won three consecutive games and 8 of 9.

ORIOLES 11, BLUE JAYS 6: Rookie Gunnar Henderson extended his torrid-hitting spree with his first career grand slam, one of four home runs launched by Baltimore in a win over visiting Toronto.

It was the fifth straight win for the Orioles, who climbed 18 games over .500 (42-24) for the first time since 2016, when they last reached the playoffs. Tampa Bay, which leads second-place Baltimore in the AL East, is the only team in the majors with a better record.

NATIONAL LEAGUE

GIANTS 11, CARDINALS 3: Mike Yastrzemski and Patrick Bailey homered and Michael Conforto added four hits and three RBI to lead San Francisco at St. Louis.

The Giants have won five straight road games and six of their last eight games overall. San Francisco won the first two games of the three-game set and claimed just their third series win in St. Louis in 10 tries since 2013.

San Francisco outfielder Mitch Haniger suffered a fractured right forearm after being hit by a pitch from Jack Flaherty in the third inning.

NOTES

BRAVES: Marcell Ozuna has avoided a serious injury to his right wrist after being hit by a pitch Monday night.

Ozuna was sent to a hospital for testing after leaving a 6-5 loss to the Detroit Tigers when he was struck by a pitch from Garrett Hill.

“It’s good, everything was negative,” Ozuna said Tuesday. “We’re going to take it day by day and see how I feel going forward.”

Ozuna originally thought he was seriously injured.

“I thought it might be broken, because it swelled up and I couldn’t grip,” he said. “But it is just a bruise, and I can grip today. I might be able to pinch-hit tonight or play tomorrow, but we’ll see.”

Ozuna is hitting .246 with 13 homers and 29 RBI in 51 games for the Braves, serving as the regular designated hitter while also seeing time in left field.

ANGELS: Infielder Brandon Drury was suspended for one game and fined by Major League Baseball for making contact with umpire Ramon De Jesus.

Drury appealed the discipline imposed by MLB senior vice president for on-field operations Michael Hill and will not have to serve the suspension until the appeal is decided. It will be heard by John McHale Jr., a special assistant to baseball Commissioner Rob Manfred.

Drury was cited for making contact while arguing balls and strikes at Texas on Monday night. He was ejected in the 10th inning after screaming in De Jesus’ face following a called third strike.

ORIOLES: First baseman Ryan Mountcastle has been placed on the 10-day injured list with vertigo, a move that came after the team anticipated his return following a three-game absence.

Mountcastle hasn’t played since June 8 in Milwaukee. Manager Brandon Hyde described his malady as an “illness” and had said Tuesday afternoon that Mountcastle wouldn’t start but would likely be available off the bench.

“He’s feeling much, much better today,” Hyde said before Baltimore faced Toronto in the opener of a three-game series.

Hours later, shortly before the opening pitch, the Orioles announced Mountcastle was on the injured list in a move retroactive to Saturday.

To fill out the roster, catcher Mark Kolozsvary was recalled from Triple-A Norfolk and pitcher Noah Denoyer was designated for assignment.

ATHLETICS: Furious Oakland Athletics fans came en masse with a single message to owner John Fisher: “SELL.”

Buddies Brian Guido and Scott Finney of Sacramento each took off early from work Tuesday because there was no way they were going to miss the festivities a couple of hours away in Oakland.

“I’ve been to only one game this year. I saw this game and I knew I had to come because I knew it was going to be very monumental and would send a message to the owner that this is what the fan base wants,” Finney said. “They want the ownership to sell the team so they can remain in Oakland.”

Thousands of frustrated, heartbroken A’s fans arrived early for tailgating and solidarity at the Oakland Coliseum ahead of a Rays-A’s matchup to both celebrate their team and protest a planned relocation to Las Vegas. They called it a reverse boycott aimed at bringing as many people as possible to the ballpark, complete with bright green “SELL” T-shirts made by local company Oaklandish.

A “We Are Here!” poster provided specific instructions for every inning such as chants of “Sell the team! Sell the team!” for the first Tampa Bay batter in the top of the inning and “Stay in Oakland!” followed by five claps for the first hitter in the bottom half.

The A’s announced a couple of hours before first pitch that they will donate all ticket revenue from the game to charity, the Alameda County Community Food Bank and Oakland Public Education Fund. Tickets were still being sold so the team planned to provide an update later in the evening.

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