LONDON — Whenever Josh Allen and the Buffalo Bills tried to rally in the fourth quarter on Sunday, Travis Etienne and the Jacksonville Jaguars had an answer.

Etienne rushed for 136 yards and two fourth-quarter touchdowns, and Jacksonville outlasted the jet-lagged Bills for a 25-20 win at Tottenham Hotspur Stadium.

“We answered the bell every time they rung it,” Etienne said.

Jaguars (3-2) may not want to leave London after getting back-to-back wins, ending Buffalo’s three-game winning streak, and proving they can hang with an AFC powerhouse.

“We as a team, I think, are figuring out that we’re very capable of winning these types of games,” Jags Coach Doug Pederson said. “It’s big. We came over here 1-2 and we’re going back 3-2.”

The Bills (3-2), who arrived in London on Friday morning, had routed their previous three opponents but looked tired at times. They rushed for only 29 yards and had a rash of injuries.

Etienne scored on a 35-yard run with just under three minutes left after carrying it in from 6 yards earlier. He also caught four passes for 48 yards. And Calvin Ridley had seven catches for 122 yards.

Allen twice brought the Bills back late in the fourth quarter. He ran it in from 3 yards to complete a 75-yard drive that took just 45 seconds, making it 25-20 before the two-minute warning.

With the Bills out of timeouts, the Jags punted to the Buffalo 6, leaving the Bills just 22 seconds. Stefon Diggs caught a pass and tried to lateral it, but Jacksonville recovered the fumble.

Allen was 27 of 40 for 359 yards and two touchdown passes and an interception. Diggs had eight catches for 121 yards and a touchdown, and Davis had six catches for 100 yards and a score.

49ERS 42, COWBOYS 10: Brock Purdy threw three of his four touchdown passes to George Kittle and San Francisco (5-0) extended its dominance over visiting Dallas (3-2).

The Niners knocked the Cowboys out of the playoffs in tight games the past two seasons, adding intrigue to this early season matchup between perceived contenders.

The rematch wasn’t even close.

The Niners led 14-0 before the Cowboys got their initial first down and were never really threatened on the way to matching a franchise record with their 15th straight regular-season win and earning their fifth 5-0 start.

Purdy calmly picked apart the league’s stingiest defense to improve to 10-0 as a starter in the NFL, and San Francisco’s defense made life difficult on Dak Prescott all night.

Prescott was sacked three times and heaved an interception into double coverage after Dallas fell behind 28-10 in the third quarter. He threw two more interceptions in the fourth quarter, with his only highlight coming on a 26-yard TD pass to KaVontae Turpin in the second quarter.

It was Dallas’ most lopsided defeat since losing 49-17 to New Orleans in 2013.

DOLPHINS 31, GIANTS 16: Rookie De’Von Achane had a 76-yard rushing touchdown, Tyreek Hill surpassed 150 yards receiving for the third time this season, and Miami (4-1) won at home.

The Dolphins’ 524 yards gave them 2,568 for the season – the most yards through the first five games of a season in NFL history.

Tua Tagovailoa was 22 of 30 for 308 yards with two touchdown passes and two interceptions.

The Giants’ Jason Pinnock returned one of the interceptions 102 yards for New York’s only touchdown.

Giants quarterback Daniel Jones left in the fourth because of a neck injury after a sack by linebacker Andrew Van Ginkel.

EAGLES 23, RAMS 14: Jalen Hurts passed for 303 yards and a touchdown and rushed for 72 yards and another score, and visiting Philadelphia (5-0) remained unbeaten.

Dallas Goedert had eight catches for 117 yards and an early TD for the Eagles, who shut out the Rams (2-3) after halftime.

Cooper Kupp made eight catches for 118 yards in the former Super Bowl MVP’s dynamic season debut for the Rams, who have lost three of four despite hanging in with three probable Super Bowl contenders.

STEELERS 17, RAVENS 10: Kenny Pickett hit George Pickens for a 41-yard touchdown with 1:17 remaining, and Pittsburgh (3-2) rallied to beat visiting Baltimore (3-2).

Pickett and the rest of Pittsburgh’s sporadic offense managed little over the game’s first 55 minutes, but a late interception by rookie cornerback Joey Porter Jr. gave the Steelers life, and Pickett responded by driving Pittsburgh 80 yards in eight plays, the last 41 coming on a rainbow down the sideline to Pickens.

The score was the Steelers’ first touchdown in nearly nine quarters, and it somehow was enough to beat the Ravens, who seemed intent on keeping Pittsburgh in the game before ultimately handing it to their longtime AFC North rivals.

Baltimore turned it over three times, including twice in the final five minutes.

CHIEFS 27, VIKINGS 20: Patrick Mahomes threw two touchdown passes in the third quarter, one to Travis Kelce after the All-Pro tight end briefly left the game because of an ankle injury, and Kansas City (4-1) won at Minnesota (1-4).

Mahomes was 31 of 41 for 281 yards and no turnovers in his most efficient performance of the season.

Kirk Cousins threw for scores to Jordan Addison and Alexander Mattison for the Vikings. They had two chances at the tying touchdown in the final five minutes, but a late hamstring injury to star wide receiver Justin Jefferson and a lack of timeouts from earlier mismanagement of the game were ultimately too much to overcome.

JETS 31, BRONCOS 21: New York (2-3) celebrated Nathaniel Hackett’s return to Denver (1-4), aided by Breece Hall’s 72-yard touchdown run and Bryce Hall’s 39-yard game-sealing scoop-and-score off Russell Wilson’s fumble in the final minute.

That gave Hackett, the Jets’ offensive coordinator who was fired after going 4-11 as Denver’s head coach last season, a measure of satisfaction, especially after new Broncos coach Sean Payton trashed him during training camp for the job he’d done in Denver.

FALCONS 21, TEXANS 19: Desmond Ridder passed and ran for touchdowns, providing an answer to those who had called for him to be benched, Younghoe Koo kicked a go-ahead 37-yard field goal as time expired, and Atlanta (3-2) snapped a two-game skid by winning at home against Houston (2-3).

Ridder’s 6-yard TD pass to rookie running back Bijan Robinson and 2-point pass to Tyler Allgeier gave the Falcons a 15-12 lead early in the fourth quarter.

Houston rookie quarterback C.J. Stroud answered with an 18-yard scoring pass to tight end Dalton Schultz that put the Texans ahead 19-18 with 1:49 remaining.

LIONS 42, PANTHERS 24: Jared Goff threw three touchdown passes in the first half and ran for a score in the fourth quarter, lifting Detroit over visiting Carolina (0-5).

The Lions are alone atop the NFC North in October or later for the first time since 2016.

Carolina turned the ball over three times in the first half – two coming on consecutive snaps – to set up Detroit up for three touchdowns and a 28-10 halftime lead.

COLTS 23, TITANS 16: Zack Moss upstaged the return of Jonathan Taylor by running for a career-high 165 yards and two scores, and Gardner Minshew was sharp in relief of the injured Anthony Richardson, leading Indianapolis (3-2) past visiting Tennessee (2-3).

The Colts snapped a seven-game home losing streak.

Richardson left because of a right shoulder injury late in the first half. Minshew was 11 of 14 for 155 yards in relief.

BENGALS 34, CARDINALS 20: Joe Burrow threw for 317 yards and three touchdown passes to Ja’Marr Chase, who finished with a season-high 192 yards receiving, and Cincinnati (2-3) won at Arizona (1-4).

It was a much-needed offensive performance for Burrow, who signed the NFL’s richest contract during the offseason but was slowed through his first four games of the season by a calf injury. He looked healthy against the Cardinals, completing 36 of 46 passes and buying time on a handful of plays with his athleticism in the pocket.

Chase set a single-game franchise record with 15 receptions.

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