PHILADELPHIA — The Philadelphia Phillies scored 12 runs for the biggest first inning in team history, with Howie Kendrick delivering a triple and single in the burst in a 17-3 victory against Washington on Saturday night.

The Phillies combined nine hits and four walks against Jeremy Guthrie and reliever Enny Romero. The Phils didn’t hit a home run in the inning, although they did have three doubles.

Philadelphia nearly matched the franchise mark for runs in an inning, set with 13 in the fourth at Cincinnati in 2003.

Maikel Franco, Michael Saunders and Tommy Joseph each knocked in a pair of runs.

Guthrie was pitching in the majors for the first time since 2015. He was lifted after Odubel Herrera’s RBI infield single made it 9-0.

CARDINALS 10, REDS 4: Aledmys Diaz hit two home runs, Michael Wacha allowed one run over six innings and host St. Louis spoiled Bronson Arroyo’s return to the majors.

Wacha (1-0) allowed three hits with six strikeouts against just one walk in his first start of the season. The Cardinals (2-3) snapped a three-game losing streak, while the Reds, who had won three straight, fell to 3-2.

Wacha struggled a year ago, going 7-7 with a 5.09 ERA in 138 innings over 27 games, but earned a spot with a strong spring.

The Reds called up Arroyo to make the start. Arroyo, 40, who spent 21/2 years out of the major leagues with elbow and shoulder troubles, allowed six earned runs on six hits over four innings.

PIRATES 6, BRAVES 4: Gregory Polanco had no trouble with R.A. Dickey’s knuckleball, getting three of his four hits and driving in a run off the starter to lead Pittsburgh to a win at home.

CUBS 11, BREWERS 6: Kris Bryant had three hits and three RBI, and Albert Almora Jr. added two hits and three RBI in a win at Milwaukee.

MARLINS 8, METS 1: J.T. Realmuto had three hits and two RBI, Marcell Ozuna had a homer and two RBI, and Adam Conley pitched five strong innings at New York.

AMERICAN LEAGUE

WHITE SOX 6, TWINS 2: Avisail Garcia went 3 for 4 with three RBI and Geovany Soto homered as host Chicago handed Minnesota its first loss of the season.

Soto’s homer was his third of the season in four games.

Garcia fell a double shy of the cycle. He had a two-run triple in the second inning against Minnesota starter Adalberto Mejia (0-1).

Garcia and Soto hit back-to-back home runs in the sixth.

The Twins (4-1) were looking to start 5-0 for the first time since 1968, but failed to find the good pitching they had in their first four wins.

ORIOLES 5, YANKEES 4: Hyun Soo Kim hit a tiebreaking RBI single off Dellin Betances in the seventh inning after a rare stolen base by slugger Mark Trumbo, and Baltimore remained the only unbeaten team in the majors by rallying for a win at home.

One day after making up a four-run deficit, the Orioles came back from being down 4-1 and improved this season to 4-0.

New York has lost 4 of 5.

ROYALS 7, ASTROS 3: Cheslor Cuthbert hit a solo homer early, and Eric Hosmer and Salvador Perez both went deep during a six-run eighth inning, helping Kansas City win at Houston.

The Royals trailed 2-1 and managed just two hits off Dallas Keuchel before Luke Gregerson (0-1) took over for the eighth.

Alex Gordon put Kansas City ahead with a two-run double, Lorenzo Cain hit an RBI single and then Hosmer’s first homer this season extended the lead to 6-2.

Two pitches later, Perez sent an 88 mph fastball into the seats in left field to chase Gregerson.

RAYS 3, BLUE JAYS 2: Toronto reliever Casey Lawrence made his major league debut and wound up walking home the winning run with two outs in the 11th inning, lifting Tampa Bay to a win at St. Petersburg, Florida.