– The Associated Press

STANFORD, Calif. – Even without Andrew Luck, Stanford still had every response it needed for Matt Barkley and Southern California.

Josh Nunes threw a go-ahead 37-yard touchdown to Zach Ertz, Stepfan Taylor ran for 153 yards and scored two touchdowns, and No. 21 Stanford upset second-ranked USC 21-14 on Saturday night for its fourth straight win in this series.

Heisman Trophy hopeful Matt Barkley threw for 254 yards and two interceptions while completing only 20 of 41 passes.

He was also sacked twice on the final drive for the Trojans (2-1, 0-1 Pac-12) and threw out of bounds on a final, desperate heave on fourth-and-39 from USC’s 25-yard line.

The Cardinal (3-0, 1-0) are 3-0 for the third straight season for the first time since 1970-72, and have their longest winning streak ever against the Trojans.

(1) ALABAMA 52, ARKANSAS 0: Eddie Lacy ran for three touchdowns and the Crimson Tide forced five turnovers in a rout at Fayettville, Ark.

A.J. McCarron was 11 of 16 passing for 189 yards and a touchdown.

Kenyan Drake, T.J. Yeldon and Blake Sims also added touchdown runs in the blowout, which was Arkansas’ worst loss since a 70-17 defeat at Southern California in 2005.

(3) LSU 63, IDAHO 14: Ronald Martin and Lavar Edwards each intercepted deflected passes and returned them for scores as LSU won easily at Baton Rouge, La.

(4) OREGON 63, TENNESSEE TECH 14: Marcus Mariota threw for 308 yards and four touchdowns before Oregon pulled its starters at Eugene, Ore. De’Anthony Thomas had 222 all-purpose yards on 10 touches.

(5) FLORIDA STATE 52, WAKE FOREST 0: Chris Thompson scored on runs of 74 and 80 yards on successive carries to lead the Seminoles at Tallahassee, Fla.

Thompson, who suffered a broken back at Wake Forest a year ago that nearly ended his career, already had a career-high 197 yards following his 80-yard touchdown run that put the Seminoles into a 28-0 lead.

(7) GEORGIA 56, FLORIDA ATLANTIC 20: Aaron Murray passed for a career-best 342 yards and two touchdowns, and also scored twice on short runs as Georgia bounced back from another slow start in a rout at Athens, Ga.

(8) SOUTH CAROLINA 49, UAB 6: Connor Shaw went 8 of 14 for 107 yards before reinjuring his throwing shoulder in a win at Columbia, S.C.

Sophomore Dylan Thompson took over again, throwing a 95-yard touchdown pass to Damiere Byrd that put South Carolina up 35-6 in the third quarter.

(9) WEST VIRGINIA 42, JAMES MADISON 12: Geno Smith completed 34 of 39 passes for 411 yards and five touchdowns as West Virginia (2-0) rolled at Landover, Md.

(11) CLEMSON 41, FURMAN 7: Tajh Boyd threw for 310 yards and three touchdown passes, and Sammy Watkins had a 58-yard touchdown run in his season debut at Clemson, S.C.

(12) OHIO STATE 35, CALIFORNIA 28: Braxton Miller lofted a 72-yard touchdown pass to Devin Smith with 3:26 left and Christian Bryant snuffed out California’s last chance with an interception for the Buckeyes (3-0) at Columbus, Ohio.

PITTSBURGH 35, (13) VIRGINIA TECH 17: Ray Graham ran for 94 yards and two scores, and added an 18-yard touchdown reception to lead Pitt (1-2) over Virginia Tech (2-1) at Pittsburgh.

Tino Sunseri passed for 283 yards and two touchdowns, and freshman running back Rushel Shell added 157 yards as Pitt gave Coach Paul Chryst his first career victory.

(15) KANSAS STATE 35, NORTH TEXAS 21: Collin Klein threw for 230 yards and accounted for three touchdowns, and Tyler Lockett returned a kickoff 96 yards for another score at Manhattan, Kan.

(16) TCU 20, KANSAS 6: Casey Pachall threw for 335 yards and two touchdowns to Brandon Carter, as TCU (2-0) won its Big 12 debut at Lawrence, Kan.

Carter finished with eight catches for 141 yards, and Waymon James added 99 yards rushing for the Horned Frogs, who pushed the nation’s longest winning streak to 10 games.

(17) MICHIGAN 63, MASSACHUSETTS 13: Denard Robinson put up 397 yards of total offense and accounted for four touchdowns at Ann Arbor, Mich.

(18) FLORIDA 37, (23) TENNESSEE 20: Jeff Driskel threw two touchdown passes and Trey Burton rushed for a pair of scores as the Gators scored the final 24 points at Knoxville.

(19) LOUISVILLE, 39, NORTH CAROLINA 34: Teddy Bridgewater threw three first-half touchdowns and Louisville (3-0) scored on its first six possessions, and then had to hold off North Carolina with a late goal-line stand at Louisville, Ky.

(20) NOTRE DAME 20, MICHIGAN STATE 3: Everett Golson threw a touchdown pass and ran for a score to help the Fighting Irish at East Lansing, Mich.

The Fighting Irish (3-0) snapped a six-game losing streak against ranked teams and beat a top-10 opponent for the first time in seven years.