AKRON, Ohio — Boston Red Sox center fielder Mookie Betts hit a single and a home run in a one-game rehab assignment, but the Portland Sea Dogs dropped a 10-3 decision Sunday against the Akron RubberDucks.

Portland (41-74) finished its road trip at 1-5 and opens a six-game homestand Tuesday against Erie.

Mike McCarthy (6-6) took the loss, giving up four hits and three earned runs in four-plus innings. Ryan Merritt (10-7) got the win, going seven innings and allowing one run.

Betts, who is on the seven-day concussion disabled list, homered to lead off the ninth off Josh Martin. He’s expected to rejoin the Red Sox for a home series starting Tuesday against the Miami Marlins.

Manuel Margot had three doubles for the Sea Dogs.

Margot helped Portland grabbed a 1-0 lead in the top of the fifth, hitting a double and stealing third before scoring on a fielder’s choice grounder by Oscar Tejeda.

But Akron answered with five runs in the bottom half. Bradley Zimmer put the RubberDucks ahead with a two-run single off reliever Mike Augliera, and Carlos Moncrief followed with a two-run homer.

The RubberDucks added five runs in the seventh against Williams Jerez, highlighted by Yandy Diaz’s two-run homer and Todd Hankins’ two-run double.

The Sea Dogs capped the scoring in the ninth on Betts’ home run and an RBI double by Margot that drove home Sam Travis.