Expect to encounter traffic delays, street closures and, most likely, blood-covered zombies in downtown Portland on Monday when filming continues on a new romantic comedy set amid a zombie outbreak.

Filming on Maine native Kyle Rankin’s “Night of the Living Deb” began last week, but most of the footage was shot in private homes and businesses. The shooting now moves outside into public view.

The city announced on its website that India Street will be open to local traffic only between Middle and Federal streets while Newbury Street will be open to local traffic only between Hampshire and Hancock streets. The closures will be in effect between 8:30 a.m. and noon and from 1 to 4:30 p.m.

City officials warned that even local traffic and buses will be delayed “while cameras are rolling.” Motorists are being encouraged to seek alternate routes.

“Night of the Living Deb” will feature some well-known veteran actors, including Michael Cassidy of the TBS sitcom “Men at Work” and Ray Wise, whose credits include “Twin Peaks,” the 1987 film “Robocop” and a recurring role on the CBS sitcom “How I Met Your Mother.” Actress Maria Thayer, who has appeared in the movies “Forgetting Sarah Marshall” and “Accepted,” has been cast as Deb.

The film is described on Facebook as a “female driven action-horror rom-com set in the world of a zombie apocalypse on Christmas.” Filming will continue through July 3.

Rankin is a native of York who has been based in Los Angeles since 2002. He graduated from the University of Maine.