BALTIMORE — Rafael Devers hit a first-inning grand slam, Kiké Hernández had four hits and the Boston Red Sox slugged their way to a 17-4 rout of the Baltimore Orioles on Saturday.

Jordan Lyles (10-10) couldn’t make it out of the fourth in his first start this month, and the Orioles lost for the fifth time in seven games. Baltimore entered four games behind Seattle for the final wild card in the American League.

Christian Arroyo hit a two-run homer in the fifth for the Red Sox, who had already broken the game open by then. Boston snapped a four-game losing streak while setting season highs for runs and hits (21), and Michael Wacha (11-1) extended his unbeaten run to 11 starts.

Lyles missed his previous turn because he was sick, and this one was bad from the beginning. A walk, a single and a hit batter loaded the bases for Devers, who cleared them with a drive to left-center field. It was his 26th homer of the year and the first of three hits on the night for the star third baseman.

Cedric Mullins went deep for the Orioles in the third, but Boston responded immediately with four more runs in the fourth. Hernández and Kevin Plawecki hit consecutive doubles to make it 5-1. With two out, Alex Verdugo hit an RBI single and then Xander Bogaerts singled to chase Lyles.

Devers singled off reliever Keegan Akin to make it 7-1, and Trevor Story followed with a run-scoring single of his own.

Lyles allowed eight runs and seven hits in 3 2/3 innings.

Wacha permitted three runs and six hits in six innings, with five strikeouts and no walks.

TRAINER’S ROOM

Red Sox: Left fielder Tommy Pham exited in the fourth because of a bruised left shin. … Story appeared to be hit by a pitch while swinging at it in the first. It was ruled a strikeout and he remained in the game. … Right-hander Nathan Eovaldi (shoulder) threw a bullpen session before the game.

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